EFFECT OF WORMWOOD (ARTEMISIA ABSINTHIUM) HYDROALCOHOLIC EXTRACT ON THE UTERUS, OVIDUCT TISSUES AND PITUITARY- GONADAL AXIS HORMONES IN NMRI MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

CHEGINI SHOKOUH; RAMZANI MINA; SHAHLA SOLMAZ

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ANIMAL ENVIRONMENT Year:2018 | Volume:10 | Issue:1 Page(s): 59-66

Download Full-Text

Persian Verion

View:

762

Download:

Cites:

Information Journal Paper

Title

EFFECT OF WORMWOOD (ARTEMISIA ABSINTHIUM) HYDROALCOHOLIC EXTRACT ON THE UTERUS, OVIDUCT TISSUES AND PITUITARY- GONADAL AXIS HORMONES IN NMRI MICE

Author(s)

CHEGINI SHOKOUH | RAMZANI MINA | SHAHLA SOLMAZ | Issue Writer Certificate

Keywords

ARTEMISIA ABSINTHIUMQ1

UTERINEQ1

OVIDUCTQ1

PITUITARY- GONADAL AXISQ1

MICEQ1

Abstract

ARTEMISIA ABSINTHIUM (known as wormwood) is used as a menstruation and abortive drug in the traditional medicine. Therefore, we have evaluated the effects of A. absinthium hydroalcoholic extract on the uterus, OVIDUCT tissues and pituitary_gonadal axis hormones in adult female NMRI MICE. In this experimental study, intraperitoneally injections were performed over 30 days on 50 female NMRI MICE with 50, 100, and 150 mg/kg.bw doses of the extract of Artemisia stem and flower. Sham group received distilled water and control group was kept without any injection. After 30 days of injections, animals were dissected and blood samples were collected by heart aspiration. The levels of LH, FSH, estrogen and progesterone serum were measured. Sections of OVIDUCT and uterus were prepared and stained by H& E method. Our findings in all experimental groups indicated a significant reduction in the body weight comparing with sham and control groups. In parameters such as uterus tissue thickness (Endometer, Miometer and Perimeter), and uterus glands, a significant decrease (p<0.05) was observed in the groups receiving 100 and 150 mg/kg doses of the extract (p<0.05). In all experimental groups, no significant changes were observed at the levels of estradiol and progesterone. FSH and LH showed a significant decrease in the groups receiving 100 and 150 mg/kg doses of the extract (p<0.05). It can be concluded that ARTEMISIA ABSINTHIUM hydroalcoholic extract in high doses has damaging effects on the reproductive system and UTERINE tissue, which may be due to α and β Thujoun, Alkaloid and Saponin constituents in this plant.

Cites

No record.

References

No record.

Cite

APA: Copy

CHEGINI, SHOKOUH, RAMZANI, MINA, & SHAHLA, SOLMAZ. (2018). EFFECT OF WORMWOOD (ARTEMISIA ABSINTHIUM) HYDROALCOHOLIC EXTRACT ON THE UTERUS, OVIDUCT TISSUES AND PITUITARY- GONADAL AXIS HORMONES IN NMRI MICE. JOURNAL OF ANIMAL ENVIRONMENT, 10(1 ), 59-66. SID. https://sid.ir/paper/206807/en

Vancouver: Copy

CHEGINI SHOKOUH, RAMZANI MINA, SHAHLA SOLMAZ. EFFECT OF WORMWOOD (ARTEMISIA ABSINTHIUM) HYDROALCOHOLIC EXTRACT ON THE UTERUS, OVIDUCT TISSUES AND PITUITARY- GONADAL AXIS HORMONES IN NMRI MICE. JOURNAL OF ANIMAL ENVIRONMENT[Internet]. 2018;10(1 ):59-66. Available from: https://sid.ir/paper/206807/en

IEEE: Copy

SHOKOUH CHEGINI, MINA RAMZANI, and SOLMAZ SHAHLA, “EFFECT OF WORMWOOD (ARTEMISIA ABSINTHIUM) HYDROALCOHOLIC EXTRACT ON THE UTERUS, OVIDUCT TISSUES AND PITUITARY- GONADAL AXIS HORMONES IN NMRI MICE,” JOURNAL OF ANIMAL ENVIRONMENT, vol. 10, no. 1 , pp. 59–66, 2018, [Online]. Available: https://sid.ir/paper/206807/en

Related Journal Papers