ASSESSMENT OF MUTAGENICITY AND CARCINOGENICITY OF EFFECTS DISPOSABLE FOOD CONTAINERS USING SALMONELLA TYPHIMURIUM STRAIN TA104

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MEHRABIAN S.; TOHIDPOUR M.; TABATABAEI R.; EMTIAZJOU HOSSEIN

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Journal: IRANIAN JOURNAL OF BIOLOGY Year:2003 | Volume:13 | Issue:3-4 Page(s): 1-7

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Title

ASSESSMENT OF MUTAGENICITY AND CARCINOGENICITY OF EFFECTS DISPOSABLE FOOD CONTAINERS USING SALMONELLA TYPHIMURIUM STRAIN TA104

Author(s)

MEHRABIAN S. | TOHIDPOUR M. | TABATABAEI R. | EMTIAZJOU HOSSEIN | Issue Writer Certificate

Keywords

MUTAGENICITY AND CARCINOGENICITYQ4

HIGH-DENSITY POLYETHYLENE (HDPE)Q4

LOW DENSITY POLYETHYLENE (LDPE)Q3

SALMONELLA TYPHIMURIUMQ3

MICROSOMEQ3

Abstract

Regarding to science and technology development, presently the application of disposable food containers which has generally been made of high and low - density polyethylene are increasing. For studying the effects of the above disposable food containers which may have on the society health, the MUTAGENICITY AND CARCINOGENICITY effects of these disposable food containers have been assessed by the Ames test. Mutagenicity assay has been done with Ames method applying SALMONELLA TYPHIMURIUM strain TA 104. By the effect of mutation this strain has been missed the histidine synthesis potential. If this strain is cultured in minimal agar medium, no growth will be seen, because histidine has not been produced. In this research, polyethylene compositions has been added separately to minimal agar medium SALMONELLA TYPHIMURIUM strain TA104 and compared to positive control index consisting of mutagen sodium azide and negative control index (distilled water). Carcinogen materials will cause a reverse mutation towards the synthesis of histidine and several bacteria will produce histidine. Their presence considering to colony numbers and comparison with negative control index containing several colonies produced by spontaneous mutation approved materials mutagenicity and compared. The obtained results showed that HOPE, disposable glass and food containers, bottle for carrying the liquids, milk plastic bags do not possess the mutagenicity property. LDPE which is generally transparent and made of monomers and free- radicals will cause reverse mutation in thin plastic bags for histidine synthesis. The plastic bags coated by liquid or solid oil will much more affected by mutagenicity. Mouse liver tissues MICROSOMEs obtained under sterile conditions have been added separately to minimal agar medium suspected to carcinogenicity and measured the effect of the carcinogen materials and bacteria status affected by reverse mutation and produced histidine.

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APA: Copy

MEHRABIAN, S., TOHIDPOUR, M., TABATABAEI, R., & EMTIAZJOU, HOSSEIN. (2003). ASSESSMENT OF MUTAGENICITY AND CARCINOGENICITY OF EFFECTS DISPOSABLE FOOD CONTAINERS USING SALMONELLA TYPHIMURIUM STRAIN TA104. IRANIAN JOURNAL OF BIOLOGY, 13(3-4), 1-7. SID. https://sid.ir/paper/21216/en

Vancouver: Copy

MEHRABIAN S., TOHIDPOUR M., TABATABAEI R., EMTIAZJOU HOSSEIN. ASSESSMENT OF MUTAGENICITY AND CARCINOGENICITY OF EFFECTS DISPOSABLE FOOD CONTAINERS USING SALMONELLA TYPHIMURIUM STRAIN TA104. IRANIAN JOURNAL OF BIOLOGY[Internet]. 2003;13(3-4):1-7. Available from: https://sid.ir/paper/21216/en

IEEE: Copy

S. MEHRABIAN, M. TOHIDPOUR, R. TABATABAEI, and HOSSEIN EMTIAZJOU, “ASSESSMENT OF MUTAGENICITY AND CARCINOGENICITY OF EFFECTS DISPOSABLE FOOD CONTAINERS USING SALMONELLA TYPHIMURIUM STRAIN TA104,” IRANIAN JOURNAL OF BIOLOGY, vol. 13, no. 3-4, pp. 1–7, 2003, [Online]. Available: https://sid.ir/paper/21216/en

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