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Information Journal Paper

Title

CLONING AND EXPRESSION OF A SCFV FROM AN ANTI HUMAN PLASMINOGEN MONOCLONAL ANTIBODY

Pages

  52-60

Abstract

 Angiogenesis is the formation of new blood vessels from existing ones. New blood vessels provide the cells with metabolic requirements. ANGIOGENESIS plays a pivotal role in many physiological and pathological phenomena. Proteinease especially plasmin is critical in degrading of matrix metalloproteinase releasing and activating different growth factor from it. ANGIOGENESIS initiate by the activation of plasminogen on the cell surface. Our previous finding indicates that an anti human plasminogen monoclonal antibody could inhibit the ANGIOGENESIS. According to importance of this antibody, we tried to make the SCFV of this antibody. SDS-PAGE and immunobloting analysis and ELISA confirmed the expression and immunological activity of the SCFV.

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  • Cite

    APA: Copy

    GHARAATI, M.R., MIRSHAHI, M., RABBANI, H., SAIFI ABOLHASSAN, M., BEHMANESH, M., & SHAMSI POOR, F.. (2013). CLONING AND EXPRESSION OF A SCFV FROM AN ANTI HUMAN PLASMINOGEN MONOCLONAL ANTIBODY. IRANIAN JOURNAL OF BIOLOGY, 26(1), 52-60. SID. https://sid.ir/paper/21505/en

    Vancouver: Copy

    GHARAATI M.R., MIRSHAHI M., RABBANI H., SAIFI ABOLHASSAN M., BEHMANESH M., SHAMSI POOR F.. CLONING AND EXPRESSION OF A SCFV FROM AN ANTI HUMAN PLASMINOGEN MONOCLONAL ANTIBODY. IRANIAN JOURNAL OF BIOLOGY[Internet]. 2013;26(1):52-60. Available from: https://sid.ir/paper/21505/en

    IEEE: Copy

    M.R. GHARAATI, M. MIRSHAHI, H. RABBANI, M. SAIFI ABOLHASSAN, M. BEHMANESH, and F. SHAMSI POOR, “CLONING AND EXPRESSION OF A SCFV FROM AN ANTI HUMAN PLASMINOGEN MONOCLONAL ANTIBODY,” IRANIAN JOURNAL OF BIOLOGY, vol. 26, no. 1, pp. 52–60, 2013, [Online]. Available: https://sid.ir/paper/21505/en

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