Synthesis of nano HA/β TCP mesoporous particles using a simple modification in granulation method in PVA/ Oil and investigation of biological response

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kermani Farzad; yousefi Abbas; kargozar Saeed; teyrani najaran ZAHRA; mollazadeh bidokhti sahar; moayed MOHAMMAD HADI

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Journal: CERAMIC SCIENCE & ENGINEERING Year:2019 | Volume:8 | Issue:1 Page(s): 13-25

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Title

Synthesis of nano HA/β TCP mesoporous particles using a simple modification in granulation method in PVA/ Oil and investigation of biological response

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Keywords

Granulation methodQ1

Mesoporous particlesQ2

HA/βTCPQ1

Granulation methodQ1

Data modelingQ1

Abstract

Granulation method in the mixture of oil, water, and PVA was used to synthesize HA/β TCP porous nano-powders. Results showed that the presence of oil in PVA/oil system results in crystallization of mesoporous HA/β TCP particles with the surface area of 93  cm2/g. Using Rietveld method, the amounts of HA/β TCP and amorphous phases in the oven-dried PVA substrate powders after heat-treatment were calculated as about 65, 13, and 22  wt. %, respectively. RSM modeling showed that TEOS is the optimum surfactant in this method. Bioactivity test showed that HA/ β TCP sample is bioactive in SBF medium. According to cell viability results, synthesized powder in the presence of oil/PVA, which was then modified by 25  wt. % of TEOS, did not cause toxicity. Using Alizarin Red S staining quantification assay, it was found that after modification by TEOS, bone-nodule formation was enhanced by 25%.

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APA: Copy

kermani, Farzad, yousefi, Abbas, kargozar, Saeed, teyrani najaran, ZAHRA, mollazadeh bidokhti, sahar, & moayed, MOHAMMAD HADI. (2019). Synthesis of nano HA/β TCP mesoporous particles using a simple modification in granulation method in PVA/ Oil and investigation of biological response. CERAMIC SCIENCE & ENGINEERING, 8(1 ), 13-25. SID. https://sid.ir/paper/227899/en

Vancouver: Copy

kermani Farzad, yousefi Abbas, kargozar Saeed, teyrani najaran ZAHRA, mollazadeh bidokhti sahar, moayed MOHAMMAD HADI. Synthesis of nano HA/β TCP mesoporous particles using a simple modification in granulation method in PVA/ Oil and investigation of biological response. CERAMIC SCIENCE & ENGINEERING[Internet]. 2019;8(1 ):13-25. Available from: https://sid.ir/paper/227899/en

IEEE: Copy

Farzad kermani, Abbas yousefi, Saeed kargozar, ZAHRA teyrani najaran, sahar mollazadeh bidokhti, and MOHAMMAD HADI moayed, “Synthesis of nano HA/β TCP mesoporous particles using a simple modification in granulation method in PVA/ Oil and investigation of biological response,” CERAMIC SCIENCE & ENGINEERING, vol. 8, no. 1 , pp. 13–25, 2019, [Online]. Available: https://sid.ir/paper/227899/en

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