مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

449
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Design and Synthesis of DNA-Templated Silver Nanoclusters for Recognition of microRNA-103

Pages

  313-319

Abstract

 MicroRNAs (miRNAs) are single-stranded RNAs that play key roles in cellular disorders or disease diagnosis. Thus the method for sensitive and selective detection of miRNAs is imperative to clinical diagnosis. Recently it has witnessed the rapid development of Metal Nanocluster-Based fluorescent probe design and its successful applications in detecting various targets, such as ssDNA, miRNA and Metal Ions. The DNA scaffolded Metal nanoclusters display excellent photostability, subnanometer size, nontoxicity, biocompatibility and thus well-suited as a fluorescent probe for biochemical applications. Here we develop a DNA/Metal Nanoclusters (MNCs)-based turn-on Fluorescence method in the presence of target MicroRNAs as a potential biomarker for screening cancer. DNA scaffold Metal nanocluster was fabricated by a one-pot wet-chemical strategy and characterized by TEM and DLS techniques. This Nanobisensor had a detection limit of 0. 64pM. Conclusion, this nanobiosensors could become a potential alternative tools for detection of miRNAs in biological samples and useful in biomedical research and early clinical diagnosis.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    AHMADI, E., Barghaii, Y.S., & HOSEINI, S.M.. (2019). Design and Synthesis of DNA-Templated Silver Nanoclusters for Recognition of microRNA-103. JOURNAL OF BIOTECHNOLOGY, 10(2 ), 313-319. SID. https://sid.ir/paper/231228/en

    Vancouver: Copy

    AHMADI E., Barghaii Y.S., HOSEINI S.M.. Design and Synthesis of DNA-Templated Silver Nanoclusters for Recognition of microRNA-103. JOURNAL OF BIOTECHNOLOGY[Internet]. 2019;10(2 ):313-319. Available from: https://sid.ir/paper/231228/en

    IEEE: Copy

    E. AHMADI, Y.S. Barghaii, and S.M. HOSEINI, “Design and Synthesis of DNA-Templated Silver Nanoclusters for Recognition of microRNA-103,” JOURNAL OF BIOTECHNOLOGY, vol. 10, no. 2 , pp. 313–319, 2019, [Online]. Available: https://sid.ir/paper/231228/en

    Related Journal Papers

    Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops





    Move to top