INDUCTION OF ESTRUS IN ANESTROUS TERRIER BY A COMBINATION OF CABERGOLINE AND HCG

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RASTEGARNIA A.; FATEHFAR M.; AMIRFALLAH A.; MORADI N.

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Journal: JOURNAL OF VETERINARY CLINICAL RESEARCH Year:2011 | Volume:2 | Issue:3 (7) Page(s): 135-146

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Title

INDUCTION OF ESTRUS IN ANESTROUS TERRIER BY A COMBINATION OF CABERGOLINE AND HCG

Author(s)

RASTEGARNIA A. | FATEHFAR M. | AMIRFALLAH A. | MORADI N. | Issue Writer Certificate

Keywords

BITCHQ3

ESTRUSQ2

CABERGOLINEQ2

HCGQ3

Abstract

In this experiment, the effect of oral administration of CABERGOLINE, an anti-prolactin drug on induction of fertile ESTRUS in BITCHes was investigated. For this purpose, fourteen BITCHes from terrier breeds were used in the study at their already determined periods of anestrous. Four dogs formed the control group, while 10 BITCHes were treatment group. All treatment females were administered with recommended doses (5 mg/day) of CABERGOLINE formulation marketed for use in women. An aqueous solution of CABERGOLINE (casber, Pharmacia, Italy) was orally administered until 2 days after the onset of proestrus or for a maximum of 41 days. The dogs with signs of proestrus (8/10) following the treatment were assigned into two subgroups. Five hundred IU of HCG was intramuscularly administered to four of these dogs on days 1 and 3 of ESTRUS. The remaining 4 dogs were not treated with HCG.Blood samples were taken once from all females during the first days of treatment and then every other day during the beginning the behavioral ESTRUS to measure progesterone concentrations. Induced ESTRUS rates and mean treatment and proestrus durations of dogs in treatment were compared. In the treatment proestrus was induced between days 21-41 (mean: 29±6.5 days), in the ratio of 80.0 (p<0.05). The duration. Of proestrus and oestrus was found to be 8.1±1.9 (range, 6 to 11).The duration of ESTRUS in the HCG (+) and HCG (-) subgroups were found to be 10.1±1.8 (range 9 to 11) and 14±2.5 (range, 8 to 12) days, respectively. The conception rate in relation to the number of BITCHes responding to the ESTRUS induction treatment was similar, 50% (2 out of 4) and mean number of offspring in the HCG (+) and HCG (-) subgroups were found to be 3.5±0.6 and 4±1.4, respectively (p>0.05). In control group, all the animals did not show ESTRUS behavior or pregnancy at the same period.It has been concluded from this study that normal and fertile ESTRUS can be induced more economically in BITCHes during different stages of anestrous using CABERGOLINE formulation marketed for use in women, and HCG injections on days 1 and 3 of the ESTRUS induced by this method had no positive effects on the pregnancy rates.

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APA: Copy

RASTEGARNIA, A., FATEHFAR, M., AMIRFALLAH, A., & MORADI, N.. (2011). INDUCTION OF ESTRUS IN ANESTROUS TERRIER BY A COMBINATION OF CABERGOLINE AND HCG. JOURNAL OF VETERINARY CLINICAL RESEARCH, 2(3 (7)), 135-146. SID. https://sid.ir/paper/232998/en

Vancouver: Copy

RASTEGARNIA A., FATEHFAR M., AMIRFALLAH A., MORADI N.. INDUCTION OF ESTRUS IN ANESTROUS TERRIER BY A COMBINATION OF CABERGOLINE AND HCG. JOURNAL OF VETERINARY CLINICAL RESEARCH[Internet]. 2011;2(3 (7)):135-146. Available from: https://sid.ir/paper/232998/en

IEEE: Copy

A. RASTEGARNIA, M. FATEHFAR, A. AMIRFALLAH, and N. MORADI, “INDUCTION OF ESTRUS IN ANESTROUS TERRIER BY A COMBINATION OF CABERGOLINE AND HCG,” JOURNAL OF VETERINARY CLINICAL RESEARCH, vol. 2, no. 3 (7), pp. 135–146, 2011, [Online]. Available: https://sid.ir/paper/232998/en

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