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Information Journal Paper

Title

EFFECTS OF DIETARY ADMINISTRATION OF HYDROALKOHALIC EXTRACT OF FERULA (FERULA ASSAFOETIDA) ON GROWTH, ANTIOXIDANT RELATED GENES EXPRESSION IN ZEBRAFISH (DANIO RERIO)

Pages

  89-98

Abstract

 The present study investigates the effect of different levels ofFerula assafoetida hydroalkohalic extract on expression of genes related to ANTIOXIDANT enzymes (SOD, CAT) and GROWTH (GH, IGF) in ZEBRAFISH (Danio rerio). For this purpose, ZEBRAFISH with average weight of 0.3+0.01 gr fed on diet supplemented with 0%, 0.5%, 1% and 2% of FERULA ASSAFOETIDA hydroalkohalic extract for 8 weeks. At the end of feeding trial, RNA extracted from liver and brain, cDNA synthesized with Reverse-Transcriptase kit and PCR were done using primers relate to SOD, CAT, GH and IGF, Beta-actin as housekeeping genes. Results showed that expression of genes related to both GROWTH and ANTIOXIDANT increased in fish fed Ferula compared to control (P<0.05) and the increase was dose dependent. The highest expression were seen in fish fed 2% extract. According to results it seems that using FERULA ASSAFOETIDA hydroalkohalic extract could have positive effects on ZEBRAFISH GROWTH and ANTIOXIDANT systems.

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    APA: Copy

    VAHEDI, F., SAFARI, R., SHABANI, A., HOSEINIFAR, H., & KOLANGI MIANDARE, HAMED. (2018). EFFECTS OF DIETARY ADMINISTRATION OF HYDROALKOHALIC EXTRACT OF FERULA (FERULA ASSAFOETIDA) ON GROWTH, ANTIOXIDANT RELATED GENES EXPRESSION IN ZEBRAFISH (DANIO RERIO). JOURNAL OF AQUACULTURE DEVELOPMENT, 12(1 ), 89-98. SID. https://sid.ir/paper/241990/en

    Vancouver: Copy

    VAHEDI F., SAFARI R., SHABANI A., HOSEINIFAR H., KOLANGI MIANDARE HAMED. EFFECTS OF DIETARY ADMINISTRATION OF HYDROALKOHALIC EXTRACT OF FERULA (FERULA ASSAFOETIDA) ON GROWTH, ANTIOXIDANT RELATED GENES EXPRESSION IN ZEBRAFISH (DANIO RERIO). JOURNAL OF AQUACULTURE DEVELOPMENT[Internet]. 2018;12(1 ):89-98. Available from: https://sid.ir/paper/241990/en

    IEEE: Copy

    F. VAHEDI, R. SAFARI, A. SHABANI, H. HOSEINIFAR, and HAMED KOLANGI MIANDARE, “EFFECTS OF DIETARY ADMINISTRATION OF HYDROALKOHALIC EXTRACT OF FERULA (FERULA ASSAFOETIDA) ON GROWTH, ANTIOXIDANT RELATED GENES EXPRESSION IN ZEBRAFISH (DANIO RERIO),” JOURNAL OF AQUACULTURE DEVELOPMENT, vol. 12, no. 1 , pp. 89–98, 2018, [Online]. Available: https://sid.ir/paper/241990/en

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