DOSE CALCULATIONS OF MICROBEAM RADIATION THERAPY (MRT) IN WATER AND HEAD EQUIVALENT PHANTOMS USING GEANT4 SIMULATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JAFARI RAZI FATEMEH; RIAZI ZAFAR; SARDARI DARIUSH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Radiation Safety and Measurement Year:2017 | Volume:5 | Issue:3 Page(s): 33-42

Download Full-Text

Persian Verion

View:

1,474

Download:

Cites:

Information Journal Paper

Title

DOSE CALCULATIONS OF MICROBEAM RADIATION THERAPY (MRT) IN WATER AND HEAD EQUIVALENT PHANTOMS USING GEANT4 SIMULATION

Author(s)

JAFARI RAZI FATEMEH | RIAZI ZAFAR | SARDARI DARIUSH | Issue Writer Certificate

Keywords

MICROBEAM RADIATION THERAPYQ1

GEANT4Q1

PEAK TO VALLEY DOSE RATIOQ1

DOSIMETRYQ1

Abstract

MICROBEAM RADIATION THERAPY (MRT) is an innovative experimental method used for radio resistant tumours such as glioma especially in pediatric cancer. In MRT, the patient is irradiated with arrays of parallel and high-intensity X-ray microbeams. The MRT offers dose profiles consisting of a pattern of peaks and valleys. The peak-to-valley dose ratio (PVDR) is the most important metric determining the effectiveness of MRT. Its value has to be maximized in normal tissue, and minimized in cancerous tissue in order to avoid any recovery. The main aim of this study is to investigate the possible effect of beam parameters on PVDR. To do so, the 3D dose distributions in water and head equivalent phantoms are computed with various microbeam configurations using GEANT4 simulation. The results show that the most promising PVDR are obtained at 100keV and ESRF spectrum. In addition, using a 300keV beam is not suitable for microbeams separation distance below 400mm. By increasing radiation field size, microbeam’s width and their separation, PVDR decreases for all energies. PVDRs in the bone rapidly fall because of the dominant photoelectric phenomenon for such a high-Z material.

Cites

No record.

References

No record.

Cite

APA: Copy

JAFARI RAZI, FATEMEH, RIAZI, ZAFAR, & SARDARI, DARIUSH. (2017). DOSE CALCULATIONS OF MICROBEAM RADIATION THERAPY (MRT) IN WATER AND HEAD EQUIVALENT PHANTOMS USING GEANT4 SIMULATION. IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT, 5(3 ), 33-42. SID. https://sid.ir/paper/246899/en

Vancouver: Copy

JAFARI RAZI FATEMEH, RIAZI ZAFAR, SARDARI DARIUSH. DOSE CALCULATIONS OF MICROBEAM RADIATION THERAPY (MRT) IN WATER AND HEAD EQUIVALENT PHANTOMS USING GEANT4 SIMULATION. IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT[Internet]. 2017;5(3 ):33-42. Available from: https://sid.ir/paper/246899/en

IEEE: Copy

FATEMEH JAFARI RAZI, ZAFAR RIAZI, and DARIUSH SARDARI, “DOSE CALCULATIONS OF MICROBEAM RADIATION THERAPY (MRT) IN WATER AND HEAD EQUIVALENT PHANTOMS USING GEANT4 SIMULATION,” IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT, vol. 5, no. 3 , pp. 33–42, 2017, [Online]. Available: https://sid.ir/paper/246899/en

Related Journal Papers