SIMULATION OF CORONARY BRACHYTHERAPY WITH 188RE RADIOACTIVE STENT AND CALCULATIG ABSORBED DOSE OF VITAL ORGANS NEAR STENT

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ABDI MOHAMADREZA; HEIDARI VIDA

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Journal: Journal of Radiation Safety and Measurement Year:2017 | Volume:5 | Issue:2 Page(s): 49-59

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Title

SIMULATION OF CORONARY BRACHYTHERAPY WITH 188RE RADIOACTIVE STENT AND CALCULATIG ABSORBED DOSE OF VITAL ORGANS NEAR STENT

Author(s)

ABDI MOHAMADREZA | HEIDARI VIDA | Issue Writer Certificate

Keywords

INTRAVASCULAR BARACHYTHERAPYQ1

RADIOACTIVE STENTQ1

ARTERY STENOSISQ1

MONTE CARLO SIMULATIONQ1

DOSE CALCULATIONQ1

Abstract

In this study, intravascular brachytherapy is simulated with Palmaz-Schatz stent, manufacturing Co. Cordis, that is radioactived with 188Re source, using the MCNPX code. Functions and dosimetric parameters, are calculated in cylindrical Coordinates and results compared with the latest standards and AAPM TG-60 group offers, published experimental data and also other performed simulations with various programs for various locations around the source and some sensitive tissues of the body.The probabilistic risks are estimated for heart treatment and sensitive tissues around the treated vessel based on the results of this simulation and the latest reports of ICRP standards. For stent 188Re with initial activity 1 mCi initial absorbed dose rate in plaque is equal to 9.35x10-6Gy/s, maximum of absorbed dose in plaque after 28 days, is almost 83 cGy and maximum of effective equivalent dose rate in plaque, with the weight factors, reported by ICRP60, approximately equal to 4.5x10-7 Sv/s is obtained. Therefore, for accessing to the suitable dose of brachytherapy, the primary activity of RADIOACTIVE STENTs should be considered about 24-30 mCi. Hence, the achievement dose of gamma ray of 188Re will be 0.27-0.32 Gy that this amount is much less than threshold of dose of gamma risk. This feature 188Re causes to use this source for therapeutic use because of beta particles emitted from them. In addition, because of having gamma ray, it is simultaneously used for diagnostic use and as gamma camera.

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APA: Copy

ABDI, MOHAMADREZA, & HEIDARI, VIDA. (2017). SIMULATION OF CORONARY BRACHYTHERAPY WITH ¹⁸⁸RE RADIOACTIVE STENT AND CALCULATIG ABSORBED DOSE OF VITAL ORGANS NEAR STENT. IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT, 5(2), 49-59. SID. https://sid.ir/paper/246913/en

Vancouver: Copy

ABDI MOHAMADREZA, HEIDARI VIDA. SIMULATION OF CORONARY BRACHYTHERAPY WITH ¹⁸⁸RE RADIOACTIVE STENT AND CALCULATIG ABSORBED DOSE OF VITAL ORGANS NEAR STENT. IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT[Internet]. 2017;5(2):49-59. Available from: https://sid.ir/paper/246913/en

IEEE: Copy

MOHAMADREZA ABDI, and VIDA HEIDARI, “SIMULATION OF CORONARY BRACHYTHERAPY WITH ¹⁸⁸RE RADIOACTIVE STENT AND CALCULATIG ABSORBED DOSE OF VITAL ORGANS NEAR STENT,” IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT, vol. 5, no. 2, pp. 49–59, 2017, [Online]. Available: https://sid.ir/paper/246913/en

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