EVALUATION OF THE EFFECTS OF INTRAMUSCULAR INJECTION OF GROWTH HORMONE ON HISTO-MORPHOMETRIC CHANGES OF GROWTH PLATE IN PRE-PUBERTAL RABBITS BONES

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HOSSEINI F.; KARIMI I.; HOSSEININEJAD M.; HABIBIAN DEHKORDI S.

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Journal: IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES Year:2017 | Volume:11 | Issue:1 Page(s): 65-70

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Title

EVALUATION OF THE EFFECTS OF INTRAMUSCULAR INJECTION OF GROWTH HORMONE ON HISTO-MORPHOMETRIC CHANGES OF GROWTH PLATE IN PRE-PUBERTAL RABBITS BONES

Author(s)

HOSSEINI F. | KARIMI I. | HOSSEININEJAD M. | HABIBIAN DEHKORDI S. | Issue Writer Certificate

Keywords

GROWTH PLATEQ2

SOMATOTROPINQ2

RABBITQ1

Abstract

This study was aimed to evaluate histopathological effects of growth hormone on GROWTH PLATE of different bones of pre-pubertal RABBITs. A total number of 16 white New-Zealand RABBITs of 2-4 months age were divided into two groups of eight, the experiment and control groups, and were then caged under the same environmental and nutritional conditions. In the experiment group, 3 Iu/Kg SOMATOTROPIN was intramuscularly injected every seven days and control group received the same amount of normal saline. At the end of study RABBITs were euthanized using anesthetic drugs and Radius, Humerus, Femur, Tibia and the first lumbar vertebrae were isolated for histomorphometric examinations. The results showed that the thickness of GROWTH PLATE of radius had no significant statistical difference between RABBITs of experiment and control groups while this parameter was statistically greater in other bones of the experiment group including femur (P=0.039), Humerus (P=0.045), Tibia (P=0.047) and the first lumbar vertebrae (P=0.023). The results of this study showed that long term, low dose SOMATOTROPIN injection to pre-pubertal RABBITs causes thickening of GROWTH PLATE and helps its longer activity during the growth period of cortical and trabecular bones although its effects is not the same for all bones.

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APA: Copy

HOSSEINI, F., KARIMI, I., HOSSEININEJAD, M., & HABIBIAN DEHKORDI, S.. (2017). EVALUATION OF THE EFFECTS OF INTRAMUSCULAR INJECTION OF GROWTH HORMONE ON HISTO-MORPHOMETRIC CHANGES OF GROWTH PLATE IN PRE-PUBERTAL RABBITS BONES. IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES, 11(1), 65-70. SID. https://sid.ir/paper/260132/en

Vancouver: Copy

HOSSEINI F., KARIMI I., HOSSEININEJAD M., HABIBIAN DEHKORDI S.. EVALUATION OF THE EFFECTS OF INTRAMUSCULAR INJECTION OF GROWTH HORMONE ON HISTO-MORPHOMETRIC CHANGES OF GROWTH PLATE IN PRE-PUBERTAL RABBITS BONES. IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES[Internet]. 2017;11(1):65-70. Available from: https://sid.ir/paper/260132/en

IEEE: Copy

F. HOSSEINI, I. KARIMI, M. HOSSEININEJAD, and S. HABIBIAN DEHKORDI, “EVALUATION OF THE EFFECTS OF INTRAMUSCULAR INJECTION OF GROWTH HORMONE ON HISTO-MORPHOMETRIC CHANGES OF GROWTH PLATE IN PRE-PUBERTAL RABBITS BONES,” IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES, vol. 11, no. 1, pp. 65–70, 2017, [Online]. Available: https://sid.ir/paper/260132/en

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