ZINC AND COPPER OXIDE NANOPARTICLES DECREASE SYNAPTOSOMAL GLUTAMATE UPTAKE: AN IN VITRO STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAFIEI SHAHRBANOO; RIAZI GHOLAM HOSSEIN; AFRASIABI ALI; KHAJELOO MOJTABA; SHAHRIARY LEILA; ESKANDARI GHAZALEH; MODARESI SEYED MOHAMAD SADEGH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS) Year:2015 | Volume:12 | Issue:1 Page(s): 87-94

Download Full-Text

View:

316

Download:

Cites:

Information Journal Paper

Title

ZINC AND COPPER OXIDE NANOPARTICLES DECREASE SYNAPTOSOMAL GLUTAMATE UPTAKE: AN IN VITRO STUDY

Author(s)

Keywords

ZINC OXIDE NANOPARTICLE

COPPER OXIDE NANOPARTICLE

SYNAPTOSOME

GLUTAMATE

EXCITOTOXICITY

Abstract

Nanoparticles (NPs) are considered as an important environmental risk factor for cognitive impairments and neurodegenerative disorders. Recent evidences have reported a GLUTAMATErgic system response against air-borne NPs. Zinc and copper oxides (ZnO and CuO) NPs are the most common metal oxide NPs in industries. The effects of these NPs on hippocampal voltage-dependent ion channels and spatial cognition have been previously studied. However, there is a lack of evidence regarding the effects of ZnO and CuO NPs on GLUTAMATErgic synapse neurotransmission in central nervous system. In the present study, the effects of ZnO and CuO NPs on GLUTAMATE (Glu) release and uptake have been investigated in isolated nerve terminals (synaptosomes). Our findings have shown that, even in high doses of ZnO and CuO NPs, no significant effect on Glu release is observed. However, a decrease has been observed in uptake of Glu. Hence, ZnO and CuO NPs can be considered as hazardous agents inducing neurodegenerative disorders through Glu EXCITOTOXICITY.

Cites

No record.

References

No record.

Cite

APA: Copy

RAFIEI, SHAHRBANOO, RIAZI, GHOLAM HOSSEIN, AFRASIABI, ALI, KHAJELOO, MOJTABA, SHAHRIARY, LEILA, ESKANDARI, GHAZALEH, & MODARESI, SEYED MOHAMAD SADEGH. (2015). ZINC AND COPPER OXIDE NANOPARTICLES DECREASE SYNAPTOSOMAL GLUTAMATE UPTAKE: AN IN VITRO STUDY. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), 12(1), 87-94. SID. https://sid.ir/paper/283027/en

Vancouver: Copy

RAFIEI SHAHRBANOO, RIAZI GHOLAM HOSSEIN, AFRASIABI ALI, KHAJELOO MOJTABA, SHAHRIARY LEILA, ESKANDARI GHAZALEH, MODARESI SEYED MOHAMAD SADEGH. ZINC AND COPPER OXIDE NANOPARTICLES DECREASE SYNAPTOSOMAL GLUTAMATE UPTAKE: AN IN VITRO STUDY. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS)[Internet]. 2015;12(1):87-94. Available from: https://sid.ir/paper/283027/en

IEEE: Copy

SHAHRBANOO RAFIEI, GHOLAM HOSSEIN RIAZI, ALI AFRASIABI, MOJTABA KHAJELOO, LEILA SHAHRIARY, GHAZALEH ESKANDARI, and SEYED MOHAMAD SADEGH MODARESI, “ZINC AND COPPER OXIDE NANOPARTICLES DECREASE SYNAPTOSOMAL GLUTAMATE UPTAKE: AN IN VITRO STUDY,” JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), vol. 12, no. 1, pp. 87–94, 2015, [Online]. Available: https://sid.ir/paper/283027/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops