ANALYTICAL EVALUATION OF STEVIOL GLYCOSIDES BY CAPILLARY ELECTROPHORESIS SUPPORTED WITH MOLECULAR DOCKING STUDIES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AYYAPPA BATHINAPATLA; KANCHI SUVARDHAN; SINGH PARVESH; SABELA MYALOWENKOSI I.; DOVEY MARTIN; BISETTY KRISHNA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS) Year:2015 | Volume:12 | Issue:1 Page(s): 127-136

Download Full-Text

View:

341

Download:

Cites:

Information Journal Paper

Title

ANALYTICAL EVALUATION OF STEVIOL GLYCOSIDES BY CAPILLARY ELECTROPHORESIS SUPPORTED WITH MOLECULAR DOCKING STUDIES

Author(s)

Keywords

STEVIOL GLYCOSIDES (REBAUDIOSIDE-A

STEVIOSIDE)

HEPTAKIS 2

6-TRI-O-METHYL BETACYCLODEXTRIN (TM-β-CD)

CAPILLARY ELECTROPHORESIS (CE)

MOLECULAR DOCKING (MD)

Abstract

This paper reports on a newly developed electrokinetic chromatographic method for the simultaneous separation and determination of steviol glycosides in real stevia samples by capillary electrophoresis and supported by molecular docking studies. Our results obtained using 30-mM heptakis- (2, 3, 6-tri-o -methyl betacyclodextrin) as a separating agent, suggest that at optimum experimental conditions the detection limits of 2.017×10-5 and 7.386×10-5 M and relative standard deviations (n=5) of 1.10 and 1.17 were obtained for rebaudioside-A and stevioside, respectively. In addition, the molecular docking studies explained to a certain extent why the separation was successful. The calculated binding free energy results for the rebaudioside-A and stevioside complexes formed with the separating agent showed that although both ligands penetrated deeply into the hydrophobic cavity of the separating agent, the presence of additional hydrogen bonding in the case of stevioside is probably responsible for its stronger binding affinity than that of rebaudioside-A.

Cites

Computational and pharmacological investigation of novel 1, 5-diaryl-1, 4-pentadien-3-one derivatives for analgesic, antiinflammatory and anticancer potential

References

No record.

Cite

APA: Copy

AYYAPPA, BATHINAPATLA, KANCHI, SUVARDHAN, SINGH, PARVESH, SABELA, MYALOWENKOSI I., DOVEY, MARTIN, & BISETTY, KRISHNA. (2015). ANALYTICAL EVALUATION OF STEVIOL GLYCOSIDES BY CAPILLARY ELECTROPHORESIS SUPPORTED WITH MOLECULAR DOCKING STUDIES. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), 12(1), 127-136. SID. https://sid.ir/paper/283036/en

Vancouver: Copy

AYYAPPA BATHINAPATLA, KANCHI SUVARDHAN, SINGH PARVESH, SABELA MYALOWENKOSI I., DOVEY MARTIN, BISETTY KRISHNA. ANALYTICAL EVALUATION OF STEVIOL GLYCOSIDES BY CAPILLARY ELECTROPHORESIS SUPPORTED WITH MOLECULAR DOCKING STUDIES. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS)[Internet]. 2015;12(1):127-136. Available from: https://sid.ir/paper/283036/en

IEEE: Copy

BATHINAPATLA AYYAPPA, SUVARDHAN KANCHI, PARVESH SINGH, MYALOWENKOSI I. SABELA, MARTIN DOVEY, and KRISHNA BISETTY, “ANALYTICAL EVALUATION OF STEVIOL GLYCOSIDES BY CAPILLARY ELECTROPHORESIS SUPPORTED WITH MOLECULAR DOCKING STUDIES,” JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), vol. 12, no. 1, pp. 127–136, 2015, [Online]. Available: https://sid.ir/paper/283036/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops