مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

THE BIOLOGICAL MONITORING OF URINARY 1-HYDROXYPYRENE BY PAH EXPOSURE AMONG SMOKERS

Pages

  439-442

Abstract

 This study examines changes in the urinary 1-HYDROXYPYRENE (1-OHP) concentration as a polycyclic aromatic hydrocarbon (PAH) metabolite related to smoking among eight volunteers. The study subjects consisted of 8 participants (2 smokers, 4 ex-smokers and 2 non-smokers; mean age 23, range 21 ~ 24 years old) in a smoking cessation program. Three urine samples were collected each week for 4 weeks from each participant to give a total of 96 urine samples. None of the participants smoked during the study period. Levels of urinary 1-OHP, as an internal dose marker of smoke containing PAHs, were measured by high performance liquid chromatography (HPLC) fluorescence detector. Urinary 1-OHP levels in the ex-smokers were decreased during the 4 weeks study period, due to ambient sources of PAH exposure. Thus, smoking cessation was only expected to result in reduction of urinary 1-OHP. Urinary 1-OHP levels were significantly correlated with the amounts of cigarettes smoked, as assessed by the questionnaire (Spearman’s correlation coefficient, r=0.23, P=0.03). This study suggested that urinary 1-OHP can be a potentially useful BIOMARKER of smoke.

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    • Cite

    APA: Copy

    LEE, K.H., & BYEON, S.H.. (2010). THE BIOLOGICAL MONITORING OF URINARY 1-HYDROXYPYRENE BY PAH EXPOSURE AMONG SMOKERS. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH (IJER), 4(3), 439-442. SID. https://sid.ir/paper/300865/en

    Vancouver: Copy

    LEE K.H., BYEON S.H.. THE BIOLOGICAL MONITORING OF URINARY 1-HYDROXYPYRENE BY PAH EXPOSURE AMONG SMOKERS. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH (IJER)[Internet]. 2010;4(3):439-442. Available from: https://sid.ir/paper/300865/en

    IEEE: Copy

    K.H. LEE, and S.H. BYEON, “THE BIOLOGICAL MONITORING OF URINARY 1-HYDROXYPYRENE BY PAH EXPOSURE AMONG SMOKERS,” INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH (IJER), vol. 4, no. 3, pp. 439–442, 2010, [Online]. Available: https://sid.ir/paper/300865/en

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