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Information Journal Paper

Title

FACILE FABRICATION AND CHARACTERIZATION OF CHITOSAN-BASED ZINC OXIDE NANOPARTICLES AND EVALUATION OF THEIR ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY

Pages

  1-11

Abstract

 The present investigation deals with the facile synthesis and characterization of CHITOSAN (CTS) -based ZINC OXIDE (ZnO) NANOPARTICLES (NPs) and their ANTIMICROBIAL activities against pathogenic microorganisms. ZnO–CTS NPs were synthesized through two different methods: nano spray drying and precipitation, using various organic compounds (citric acid, glycerol, starch and whey powder) as stabilizers. Both the synthesis methods were simple and were devoid of any chemical usage. The detailed characterization of the NPs was carried out using UV–Vis spectroscopy, dynamic light scattering particle size analysis, zeta potential measurements and scanning electron microscopy, which confirmed the fabrication of NPs with different shapes and sizes. ANTIMICROBIAL assay of synthesized ZnO–CTS NPs was carried out against different pathogenic microbial strains (Candida albicans, Micrococcus luteusand Staphylococcus aureus). The significant (p<0.05) inhibition of growth was observed for both M. luteus and S. aureus with ZnO–CTS NPs (with a concentration ranging from 0.625 to 0.156 mg/ml) as compared to control treatment. ZnO–CTS NPs also showed significant biofilm inhibition activity (p<0.05) against M.luteusand S. aureus. The study demonstrated the potential of ZnO–CTS NPs as ANTIMICROBIAL and ANTIBIOFILM agents.

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    Cite

    APA: Copy

    DHILLON, GURPREET SINGH, KAUR, SURINDER, & BRAR, SATINDER KAUR. (2014). FACILE FABRICATION AND CHARACTERIZATION OF CHITOSAN-BASED ZINC OXIDE NANOPARTICLES AND EVALUATION OF THEIR ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY. INTERNATIONAL NANO LETTERS (INL), 4(2), 1-11. SID. https://sid.ir/paper/321470/en

    Vancouver: Copy

    DHILLON GURPREET SINGH, KAUR SURINDER, BRAR SATINDER KAUR. FACILE FABRICATION AND CHARACTERIZATION OF CHITOSAN-BASED ZINC OXIDE NANOPARTICLES AND EVALUATION OF THEIR ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY. INTERNATIONAL NANO LETTERS (INL)[Internet]. 2014;4(2):1-11. Available from: https://sid.ir/paper/321470/en

    IEEE: Copy

    GURPREET SINGH DHILLON, SURINDER KAUR, and SATINDER KAUR BRAR, “FACILE FABRICATION AND CHARACTERIZATION OF CHITOSAN-BASED ZINC OXIDE NANOPARTICLES AND EVALUATION OF THEIR ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY,” INTERNATIONAL NANO LETTERS (INL), vol. 4, no. 2, pp. 1–11, 2014, [Online]. Available: https://sid.ir/paper/321470/en

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