SERUM C-REACTIVE PROTEIN IN ASTHMA AND ITS ABILITY IN PREDICTING ASTHMA CONTROL, A CASE-CONTROL STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MONADI MAHMOUD; FIROUZJAHI ALIREZA; HOSSEINI AMIN; JAVADIAN YAHYA; SHARBATDARAN MAJID; HEIDARI BEHZAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: AMIRKABIR Year:2016 | Volume:7 | Issue:1 Page(s): 37-42

Download Full-Text

View:

240

Download:

187

Cites:

Information Journal Paper

Title

SERUM C-REACTIVE PROTEIN IN ASTHMA AND ITS ABILITY IN PREDICTING ASTHMA CONTROL, A CASE-CONTROL STUDY

Author(s)

Keywords

ASTHMA

ASTHMA CONTROL

HIGH SENSITIVE C-REACTIVE PROTEIN

PREDICTION

Abstract

Background: Increased serum HIGH SENSITIVE C-REACTIVE PROTEIN (hs-CRP) in ASTHMA and its association with disease severity has been investigated in many studies. This study aimed to determine serum hs-CRP status in ASTHMA versus healthy controls and to examine its ability in predicting ASTHMA control.Methods: Serum CRP was measured by ELISA method using a high sensitive CRP kit. Severity of ASTHMA was determined using ASTHMA Control Test. Spearman and chi square tests were used for association and correlation respectively. The predictive ability was determined by receiver operating characteristics (ROC) analysis. Accuracy was determined by determination of area under the ROC curve (AUC).Results: A total of 120 patients and 115 controls were studied. Median serum hs-CRP in ASTHMA was higher than control (P=0.001. In well controlled ASTHMA the hs-CRP decreased significantly compared with poorly controlled (P=0.024) but still was higher than control (P=0.017). Serum hs-CRP at cutoff level of 1.45 mg/L differentiated the patients and controls with accuracy of 63.5 % (AUC=0.635±0.037, P=0.001). Serum hs-CRP£2.15 mg/L predicted well controlled ASTHMA with accuracy of 62.5% (AUC=0.625±0.056, p=0.025). After adjusting for age, sex, weight and smoking, there was an independent association between serum hs-CRP>1.45 mg/L and ASTHMA by adjusted OR=2.49, p=0.018).Conclusion: These findings indicate that serum hs-CRP in ASTHMA is higher than healthy control and increases with severity of ASTHMA and decreases with. Thus, serum hs-CRP measurement can be helpful in predicting ASTHMA control and treatment response.

Cites

No record.

References

No record.

Cite

APA: Copy

MONADI, MAHMOUD, FIROUZJAHI, ALIREZA, HOSSEINI, AMIN, JAVADIAN, YAHYA, SHARBATDARAN, MAJID, & HEIDARI, BEHZAD. (2016). SERUM C-REACTIVE PROTEIN IN ASTHMA AND ITS ABILITY IN PREDICTING ASTHMA CONTROL, A CASE-CONTROL STUDY. AMIRKABIR, 7(1), 37-42. SID. https://sid.ir/paper/323385/en

Vancouver: Copy

MONADI MAHMOUD, FIROUZJAHI ALIREZA, HOSSEINI AMIN, JAVADIAN YAHYA, SHARBATDARAN MAJID, HEIDARI BEHZAD. SERUM C-REACTIVE PROTEIN IN ASTHMA AND ITS ABILITY IN PREDICTING ASTHMA CONTROL, A CASE-CONTROL STUDY. AMIRKABIR[Internet]. 2016;7(1):37-42. Available from: https://sid.ir/paper/323385/en

IEEE: Copy

MAHMOUD MONADI, ALIREZA FIROUZJAHI, AMIN HOSSEINI, YAHYA JAVADIAN, MAJID SHARBATDARAN, and BEHZAD HEIDARI, “SERUM C-REACTIVE PROTEIN IN ASTHMA AND ITS ABILITY IN PREDICTING ASTHMA CONTROL, A CASE-CONTROL STUDY,” AMIRKABIR, vol. 7, no. 1, pp. 37–42, 2016, [Online]. Available: https://sid.ir/paper/323385/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops