TYROSINASE INHIBITORY ACTIVITY WITHIN HEXANE EXTRACT OF TEN SCREENED PLANTS FROM KURDISTAN PROVINCE OF IRAN

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HASHEMI FARIDEH; ZAREI MOHAMMAD ALI

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Journal Paper

Paper Information

Journal: INTERNATIONAL JOURNAL OF ADVANCED BIOLOGICAL AND BIOMEDICAL RESEARCH (IJABBR) Year:2014 | Volume:2 | Issue:11 Page(s): 2795-2799

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Title

TYROSINASE INHIBITORY ACTIVITY WITHIN HEXANE EXTRACT OF TEN SCREENED PLANTS FROM KURDISTAN PROVINCE OF IRAN

Author(s)

HASHEMI FARIDEH | ZAREI MOHAMMAD ALI | Issue Writer Certificate

Keywords

TYROSINASE

HEXANE EXTRACT

INHIBITION

GUNDELIA

TOURNEFORTI L

Abstract

Objective: TYROSINASE as the key enzyme in melanin biosynthesis, involves in determining the color of mammalian skin and hair. A variety of dermatological disorders, come up from an unnecessary level of epidermal pigmentation. Plants are low-cost and rich sources of active compounds.Methods: More than seventy native plants collected from the central region of Kurdistan province collected. Inhibitory effect of HEXANE EXTRACTs from aerial parts of them was tested on TYROSINASE activity. All extracts were screened for their TYROSINASE inhibitory activity at 1, 0.1, 0.01, 0.001 µg/ml concentrations. Assay method was based on Microplate spectrophotometric study of absorption in 492 nm, arbutin and kojic acid were used as positive controls.Results: Among the evaluated HEXANE EXTRACTs, only 10 cases showed more than 50% TYROSINASE inhibitory activities, including GUNDELIA TOURNEFORTI L., Astragalus vegetus Bunge, Vicia hyrcanica Fisch. & C.A. Mey, Campanula involucrate Auch.ex DC, Isatis cappadocica Desv, Sanguisorba minor Scop., Eremostachys laevigata Bunge, Ballota nigra L., Aristolochia bottae Jaub.& Spach, Astragalus caryolobus Bge, and among them GUNDELIA Tournefortii L. L., showed considerable INHIBITION with IC50 of 0.173 mg/ml. These results suggest that the most effective plant extracts, especially that of GUNDELIA TOURNEFORTI L. be worthy of further investigation.

Cites

Tyrosinase Inhibition, Antioxidant Activity and GC-MS Analysis of the Hexane Extracts of the Aerial Parts of Astragalus vegetus Bungi. and Gundelia turnifortii L.

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APA: Copy

HASHEMI, FARIDEH, & ZAREI, MOHAMMAD ALI. (2014). TYROSINASE INHIBITORY ACTIVITY WITHIN HEXANE EXTRACT OF TEN SCREENED PLANTS FROM KURDISTAN PROVINCE OF IRAN. INTERNATIONAL JOURNAL OF ADVANCED BIOLOGICAL AND BIOMEDICAL RESEARCH (IJABBR), 2(11), 2795-2799. SID. https://sid.ir/paper/339149/en

Vancouver: Copy

HASHEMI FARIDEH, ZAREI MOHAMMAD ALI. TYROSINASE INHIBITORY ACTIVITY WITHIN HEXANE EXTRACT OF TEN SCREENED PLANTS FROM KURDISTAN PROVINCE OF IRAN. INTERNATIONAL JOURNAL OF ADVANCED BIOLOGICAL AND BIOMEDICAL RESEARCH (IJABBR)[Internet]. 2014;2(11):2795-2799. Available from: https://sid.ir/paper/339149/en

IEEE: Copy

FARIDEH HASHEMI, and MOHAMMAD ALI ZAREI, “TYROSINASE INHIBITORY ACTIVITY WITHIN HEXANE EXTRACT OF TEN SCREENED PLANTS FROM KURDISTAN PROVINCE OF IRAN,” INTERNATIONAL JOURNAL OF ADVANCED BIOLOGICAL AND BIOMEDICAL RESEARCH (IJABBR), vol. 2, no. 11, pp. 2795–2799, 2014, [Online]. Available: https://sid.ir/paper/339149/en

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