DIACEREIN: A POTENTIAL THERAPEUTIC DRUG FOR THE MANAGEMENT OF EXPERIMENTAL PERIODONTITIS IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOSTAFA ZAKI BASMA; MAHMOUD ENJI AHMED; ALY AZZA AHMED

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ELECTRONIC PHYSICIAN Year:2015 | Volume:7 | Issue:5 Page(s): 1290-1295

Download Full-Text

View:

227

Download:

Cites:

Information Journal Paper

Title

DIACEREIN: A POTENTIAL THERAPEUTIC DRUG FOR THE MANAGEMENT OF EXPERIMENTAL PERIODONTITIS IN RATS

Author(s)

MOSTAFA ZAKI BASMA | MAHMOUD ENJI AHMED | ALY AZZA AHMED | Issue Writer Certificate

Keywords

DIACEREIN

EXPERIMENTAL

PERIODONTITIS

RATS

Abstract

Introduction: Knowledge about the pathogenic process in the progression of periodontal disease indicates that the central cause of periodontal disease is the loss of a healthy balance between microbial virulence factors and the host’s inflammatory response. The aim of this study was to evaluate the potential effectiveness of DIACEREIN as an anti-inflammatory drug in the management of EXPERIMENTAL PERIODONTITIS in RATS.Methods: The study included 60 albino RATS that were divided into two groups. PERIODONTITIS was induced in both groups. The drug group received systemic administration of DIACEREIN, and the control group received a placebo. IL-1b was measured two weeks after the induction of PERIODONTITIS and before the administration of the drug (baseline measurement), and it was measured again at the end of two and end of four weeks after scaling and root planning and DIACEREIN administration.Results: The results indicated that there was a significant decrease in IL-1 b level in both groups. For the control group, there were significant decreases of the IL-1 b values from the baseline to two weeks and also from the baseline to four weeks, with p-values of 0.0001 for both comparisons. The same results were obtained for the drug group.Conclusion: It was concluded that it is likely that DIACEREIN may play a therapeutic role as a potent anti-inflammatory drug in the management of PERIODONTITIS.

Cites

No record.

References

No record.

Cite

APA: Copy

MOSTAFA ZAKI, BASMA, MAHMOUD, ENJI AHMED, & ALY, AZZA AHMED. (2015). DIACEREIN: A POTENTIAL THERAPEUTIC DRUG FOR THE MANAGEMENT OF EXPERIMENTAL PERIODONTITIS IN RATS. ELECTRONIC PHYSICIAN, 7(5), 1290-1295. SID. https://sid.ir/paper/345364/en

Vancouver: Copy

MOSTAFA ZAKI BASMA, MAHMOUD ENJI AHMED, ALY AZZA AHMED. DIACEREIN: A POTENTIAL THERAPEUTIC DRUG FOR THE MANAGEMENT OF EXPERIMENTAL PERIODONTITIS IN RATS. ELECTRONIC PHYSICIAN[Internet]. 2015;7(5):1290-1295. Available from: https://sid.ir/paper/345364/en

IEEE: Copy

BASMA MOSTAFA ZAKI, ENJI AHMED MAHMOUD, and AZZA AHMED ALY, “DIACEREIN: A POTENTIAL THERAPEUTIC DRUG FOR THE MANAGEMENT OF EXPERIMENTAL PERIODONTITIS IN RATS,” ELECTRONIC PHYSICIAN, vol. 7, no. 5, pp. 1290–1295, 2015, [Online]. Available: https://sid.ir/paper/345364/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops