MODELING SPATIAL DISTRIBUTION OF INTRACELLULAR ORGANELLES BY MOLECULAR MOTORS

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MOAYED F.; NAEIMPOUR F.; JAMALI YOUSEF

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Journal: Journal of Chemical and Petroleum Engineering Year:2010 | Volume:43 | Issue:2 Page(s): 51-63

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Title

MODELING SPATIAL DISTRIBUTION OF INTRACELLULAR ORGANELLES BY MOLECULAR MOTORS

Author(s)

MOAYED F. | NAEIMPOUR F. | JAMALI YOUSEF | Issue Writer Certificate

Keywords

BIONANOTECHNOLOGYQ3

MOLECULAR MOTORQ2

INTRACELLULAR TRANSPORTQ3

SPATIAL DISTRIBUTIONQ3

KINESINQ3

DYNEINQ3

MYOSINQ3

Abstract

The interface of nano-and biotechnology is a new field of research came into action with developments in various branches of nanotechnology. Mimicking natural nanosystems including nanoscale MOLECULAR MOTORs has attracted the attention of many researchers. MOLECULAR MOTORs considered in this research are nanoscale proteins holding interacellular transportation which are consisted of KINESIN, DYNEIN and MYOSIN. Many efforts have been made to model and simulate the behavior of MOLECULAR MOTORs focusing either on dynamics of individual motors or macroscopic behavior of motors or organelles using density variations. In this research, the intracellular mass transport by MOLECULAR MOTORs is investigated using a macroscopic approach based on Dinh and co-workers model reporting a generalized theory for spatial patterns of intracellular organelles exhibiting one of the four distinct patterns, namely aggregation, hyperdispersion, radial dispersion and areal dispersion. Dinh and co-workers approximated the set of differential equations describing the system with an advection-diffusion equation for which the solution was given only by introducing the 4 distribution regimes. In this work in addition to presenting the numerical solution of the approximated equation, the set of differential equations describing the distribution of 15 organelles at 4 different regimes has been numerically solved using two sets of boundary conditions. It was found that the results are sensitive to boundary conditions.

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APA: Copy

MOAYED, F., NAEIMPOUR, F., & JAMALI, YOUSEF. (2010). MODELING SPATIAL DISTRIBUTION OF INTRACELLULAR ORGANELLES BY MOLECULAR MOTORS. JOURNAL OF CHEMICAL AND PETROLEUM ENGINEERING (JOURNAL OF FACULTY OF ENGINEERING), 43(2), 51-63. SID. https://sid.ir/paper/355989/en

Vancouver: Copy

MOAYED F., NAEIMPOUR F., JAMALI YOUSEF. MODELING SPATIAL DISTRIBUTION OF INTRACELLULAR ORGANELLES BY MOLECULAR MOTORS. JOURNAL OF CHEMICAL AND PETROLEUM ENGINEERING (JOURNAL OF FACULTY OF ENGINEERING)[Internet]. 2010;43(2):51-63. Available from: https://sid.ir/paper/355989/en

IEEE: Copy

F. MOAYED, F. NAEIMPOUR, and YOUSEF JAMALI, “MODELING SPATIAL DISTRIBUTION OF INTRACELLULAR ORGANELLES BY MOLECULAR MOTORS,” JOURNAL OF CHEMICAL AND PETROLEUM ENGINEERING (JOURNAL OF FACULTY OF ENGINEERING), vol. 43, no. 2, pp. 51–63, 2010, [Online]. Available: https://sid.ir/paper/355989/en

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