Cytogenetic Analysis of 13 Iranian Women with Premature Ovarian Failure

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HADIPOUR F.; HADIPOUR Z.; MOUSAVI F.; BAGHERIZADEH I.; SHAFAGHATI Y.; BEHJATI F.

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Journal Paper

Paper Information

Journal: SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE) Year:2017 | Volume:2 | Issue:2 Page(s): 133-136

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Title

Cytogenetic Analysis of 13 Iranian Women with Premature Ovarian Failure

Author(s)

Keywords

Cytogenetics

Diffusion

Premature Ovarian Failure

Prevalence

Chromosomal Abnormality

Abstract

Patients Information Considering the clinical importance and the deep impact of Premature Ovarian Failure (POF) on the life of affected people and the important role of genetics in its development, this study was conducted to determine the frequency and type of chromosomal abnormalities in Iranian women referred to Sarem Hospital with Premature Ovarian Failure. Karyotype analysis and its association with phenotype were performed on 13 Iranian women with confirmed Premature Ovarian Failure. The metaphase chromosomes were prepared and analyzed with G-bonding technique and mosaicism of 100 cells from lymphocyte cells was studied. Finally, chromosomal abnormalities were diagnosed in 2 of 13 patients (15. 38%) with Premature Ovarian Failure. A patient with chromosomal mosaicism was [42] XX, 46 / [8] X, 45. The second patient had a translocation between chromosome X and chromosome 9, that was 46, XX, t(X, 9)(q22. 1; q22, 1). Conclusion The overall Prevalence of chromosomal abnormalities is 15. 38% among patients with Premature Ovarian Failure, which is confirmed by our findings in the chromosomal examination of these women.

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APA: Copy

HADIPOUR, F., HADIPOUR, Z., MOUSAVI, F., BAGHERIZADEH, I., & SHAFAGHATI, Y.. (2017). Cytogenetic Analysis of 13 Iranian Women with Premature Ovarian Failure. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), 2(2 ), 133-136. SID. https://sid.ir/paper/380683/en

Vancouver: Copy

HADIPOUR F., HADIPOUR Z., MOUSAVI F., BAGHERIZADEH I., SHAFAGHATI Y.. Cytogenetic Analysis of 13 Iranian Women with Premature Ovarian Failure. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2017;2(2 ):133-136. Available from: https://sid.ir/paper/380683/en

IEEE: Copy

F. HADIPOUR, Z. HADIPOUR, F. MOUSAVI, I. BAGHERIZADEH, and Y. SHAFAGHATI, “Cytogenetic Analysis of 13 Iranian Women with Premature Ovarian Failure,” SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), vol. 2, no. 2 , pp. 133–136, 2017, [Online]. Available: https://sid.ir/paper/380683/en

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