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Information Journal Paper

Title

Retrospective assessment of radiation dose by Fluorescence In Situ Hybridization and evaluation of stable chromosomal aberrations

Pages

  29-36

Abstract

 Estimation of absorbed dose for radiation workers or person involved in different radiological accident is the aim of biodosimetry. Cytogenetic methods are the most current and applicable biodosimetry tools. In chronic or protracted exposure, fluorescence in situ hybridization (FISH), Stable chromosomal aberration is used for estimation of absorbed dose. For precise estimation of absorbed dose, every biodosimetry department should prepare standard dose response curve for different dose and dose rates. In this study, after sampling of blood from two healthy males, blood samples irradiated with X-ray of linear accelerator (0. 5-2 Gy) and after separation of their lymphocytes, culturing and metaphase spread were prepared. Fluorescence in situ hybridization painting was performed and Stable chromosomal aberration was recorded. Dose response curve was prepared for Stable chromosomal aberration for different X-ray doses which can use for retrospective biodosimetry in occupational and accidental situations.

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  • Cite

    APA: Copy

    HAERI, ABOLGHASEM. (2020). Retrospective assessment of radiation dose by Fluorescence In Situ Hybridization and evaluation of stable chromosomal aberrations. IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT, 8(1 ), 29-36. SID. https://sid.ir/paper/380875/en

    Vancouver: Copy

    HAERI ABOLGHASEM. Retrospective assessment of radiation dose by Fluorescence In Situ Hybridization and evaluation of stable chromosomal aberrations. IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT[Internet]. 2020;8(1 ):29-36. Available from: https://sid.ir/paper/380875/en

    IEEE: Copy

    ABOLGHASEM HAERI, “Retrospective assessment of radiation dose by Fluorescence In Situ Hybridization and evaluation of stable chromosomal aberrations,” IRANIAN JOURNAL OF RADIATION SAFETY AND MEASUREMENT, vol. 8, no. 1 , pp. 29–36, 2020, [Online]. Available: https://sid.ir/paper/380875/en

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