Correlation between Estradiol Levels and Insulin Resistance in Patients with Polycystic Ovary Syndrome

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Khosromehr M.; ALIREZAEI M.

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Paper Information

Journal: SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE) Year:2019 | Volume:4 | Issue:3 Page(s): 149-154

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Information Journal Paper

Title

Correlation between Estradiol Levels and Insulin Resistance in Patients with Polycystic Ovary Syndrome

Author(s)

Khosromehr M. | ALIREZAEI M. | Issue Writer Certificate

Keywords

Polycystic Ovary Syndrome

Insulin Resistance

Estradiol

Abstract

Aims Polycystic Ovary Syndrome (PCOS) causes metabolic disorders and endocrine disruptions in the body. Serum levels of some hormones in this disease are abnormal, including increased levels of Estradiol in the blood. On the other hand, women with PCOS have Insulin Resistance. The aim of this study was to evaluate the correlation between Estradiol and insulin levels in PCOS patients referred to Sarem Hospital. Instrument & Methods This descriptive cross-sectional study was performed on 567 patients with PCOS referring to the infertility clinic of Sarem Hospital. Demographic and disease information was collected through a questionnaire and the results were analyzed by SPSS 22 software. Findings There was a significant correlation between BMI and fasting (p=0. 0001) and 2hpp (p=0. 001) insulin. Also a weak and inverse correlation was observed between fasting insulin and prolactin levels (p=0. 005). There was a weak correlation between fasting (p=0. 004) and 2hpp (p=0. 0001) insulin levels and menstrual cycle. There was no statistically significant correlation between serum Estradiol levels and fasting and 2hpp insulin (p>0. 05). Conclusion There is no correlation between blood Estradiol levels and Insulin Resistance and increased fasting and 2hpp blood insulin levels in patients with PCOS that lead to Insulin Resistance in these individuals cannot be used alone as a criterion of PCOS.

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APA: Copy

Khosromehr, M., & ALIREZAEI, M.. (2019). Correlation between Estradiol Levels and Insulin Resistance in Patients with Polycystic Ovary Syndrome. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), 4(3 ), 149-154. SID. https://sid.ir/paper/387949/en

Vancouver: Copy

Khosromehr M., ALIREZAEI M.. Correlation between Estradiol Levels and Insulin Resistance in Patients with Polycystic Ovary Syndrome. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2019;4(3 ):149-154. Available from: https://sid.ir/paper/387949/en

IEEE: Copy

M. Khosromehr, and M. ALIREZAEI, “Correlation between Estradiol Levels and Insulin Resistance in Patients with Polycystic Ovary Syndrome,” SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), vol. 4, no. 3 , pp. 149–154, 2019, [Online]. Available: https://sid.ir/paper/387949/en

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