Polyethylene Glycol (PEG-400): As Efficient Reaction Medium for the Synthesis of 1, 5-Dihydropyrano[2, 3-c]chromene Derivatives

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Abaszadeh Mehdi; ASADIPOUR ALI

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Journal: JOURNAL OF APPLIED CHEMISTRY Year:2018 | Volume:13 | Issue:48 Page(s): 285-293

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Title

Polyethylene Glycol (PEG-400): As Efficient Reaction Medium for the Synthesis of 1, 5-Dihydropyrano[2, 3-c]chromene Derivatives

Author(s)

Abaszadeh Mehdi | ASADIPOUR ALI | Issue Writer Certificate

Keywords

Polyethylene glycolQ1

1Q2

5-dihydropyrano[2Q1

3-c]chromenesQ1

three-component reactionQ1

catalyst-free conditionsQ1

Abstract

In this research, a simple and effective method for the synthesis of 1, 5-dihydropyrano[2, 3-c]chromene multi-substituted derivatives has been introduced, using the three-component reaction of aromatic aldehydes, malononitrile and 3-hydroxycoumarin at room temperature and in the presence of Polyethylene glycol (PEG-400) as solvent and reaction catalyst. Easy method, short reaction time, high atom economy, high yields, environmental acceptability and the easy of separating of Polyethylene glycol are included as the most important advantages of this method. Moreover, the produced products were obtained through simple filtering and no need to column and technique chromatography with high purity. Moreover, the produced products were obtained through simple filtering and no need to column and technique chromatography with high purity.

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APA: Copy

Abaszadeh, Mehdi, & ASADIPOUR, ALI. (2018). Polyethylene Glycol (PEG-400): As Efficient Reaction Medium for the Synthesis of 1, 5-Dihydropyrano[2, 3-c]chromene Derivatives. JOURNAL OF APPLIED CHEMISTRY, 13(48 ), 285-293. SID. https://sid.ir/paper/401032/en

Vancouver: Copy

Abaszadeh Mehdi, ASADIPOUR ALI. Polyethylene Glycol (PEG-400): As Efficient Reaction Medium for the Synthesis of 1, 5-Dihydropyrano[2, 3-c]chromene Derivatives. JOURNAL OF APPLIED CHEMISTRY[Internet]. 2018;13(48 ):285-293. Available from: https://sid.ir/paper/401032/en

IEEE: Copy

Mehdi Abaszadeh, and ALI ASADIPOUR, “Polyethylene Glycol (PEG-400): As Efficient Reaction Medium for the Synthesis of 1, 5-Dihydropyrano[2, 3-c]chromene Derivatives,” JOURNAL OF APPLIED CHEMISTRY, vol. 13, no. 48 , pp. 285–293, 2018, [Online]. Available: https://sid.ir/paper/401032/en

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