Design and Scale-up of Mixed Bioreactors Using Computer Simulation

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Gharanjik MohammadAmin; AMANI HOSSEIN

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Paper Information

Journal: Nashrieh Shimi va Mohandesi Shimi Iran Year:2020 | Volume:38 | Issue:4 (94) Page(s): 299-308

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Information Journal Paper

Title

Design and Scale-up of Mixed Bioreactors Using Computer Simulation

Author(s)

Gharanjik MohammadAmin | AMANI HOSSEIN | Issue Writer Certificate

Keywords

Scale-upQ1

BioreactorQ1

SimulationQ2

Laboratory ScaleQ1

Industrial ScaleQ1

SoftwareQ1

Abstract

One of the problems in the biotechnology industry is the discrepancy between the experimental results and the pilot results. Therefore, in this research, the Scale-up of Bioreactors as one of the main issues in the industrialization of laboratory research is discussed. In this research, Scale-up calculations based on Reynolds number and momentum factors, blade speed (NDi and N), and constant mass transfer mass coefficient (KLa) are investigated. Since Simulations of these criteria are manually time-consuming, computer Simulation is essential. Therefore, in the present study, the Scale-up of mixed Bioreactors was simulated by excel Software. Results of this research for Scale-up of a Bioreactor from 100 liters to 125 liters and from 80 liters to 10000 with other researchers were compared and confirmed. However, using this Software, you can make the optimization on a larger scale in the shortest possible time, which reduces costs such as optimization costs, labor costs, and more. Also, the use of this Software can help engineers to make predictions on larger-scale production.

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APA: Copy

Gharanjik, MohammadAmin, & AMANI, HOSSEIN. (2020). Design and Scale-up of Mixed Bioreactors Using Computer Simulation. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), 38(4 (94) ), 299-308. SID. https://sid.ir/paper/402538/en

Vancouver: Copy

Gharanjik MohammadAmin, AMANI HOSSEIN. Design and Scale-up of Mixed Bioreactors Using Computer Simulation. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN)[Internet]. 2020;38(4 (94) ):299-308. Available from: https://sid.ir/paper/402538/en

IEEE: Copy

MohammadAmin Gharanjik, and HOSSEIN AMANI, “Design and Scale-up of Mixed Bioreactors Using Computer Simulation,” NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), vol. 38, no. 4 (94) , pp. 299–308, 2020, [Online]. Available: https://sid.ir/paper/402538/en

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