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Information Journal Paper

Title

Effect of Coenzyme Q10 on testicular tissue after correction of experimental cryptorchidism in rat

Pages

  169-184

Abstract

 Perturbation of testicular descent into the scrotum results in Cryptorchidism. After surgical correction of Cryptorchidism (Orchidopexy), recovery of damaged testicular tissue is observed gradually. The aim of the present study was to histologically evaluate the effect of Coenzyme Q10 on testicular tissue after Orchidopexy in the Rat. In this study, 40 male immature Rats were randomly divided into 4 groups of 10 animals each. The first group received no surgical intervention. Experimental bilateral Cryptorchidism was induced surgically in the second group and Rats were kept until the end of the experiment. In the third and fourth groups, Orchidopexy was performed 35 days after induction of experimental bilateral Cryptorchidism. Rats in the third and fourth group were administered oral olive oil and Coenzyme Q10 respectively for 30 days after Orchidopexy. At the end of the experimental period, testicular tissue samples were obtained for morphologic and histomorphometerical studies. The results were analyzed with one-way ANOVA and Tukey test and p<0. 05 was considered significant. Results indicated that using Coenzyme Q10 acceleRated the repaire process of testicular injuries after Orchidopexy. The diameter of seminiferous tubules and thickness of epithelium of tubules were increased and spermatogenic indices including tubular differentiation index, repopulation index and spermiogenesis index significantly increased (p<0. 05). This study indicated that the use of Coenzyme Q10 causes testicular tissue repair and improves histomorphometrical and spermatogenesis coefficients after Orchidopexy in the Rat.

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    APA: Copy

    SHEKARI, A., SAFAVI, S.E., & MOUSAVI, GH.. (2020). Effect of Coenzyme Q10 on testicular tissue after correction of experimental cryptorchidism in rat. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), 14(2 (54) ), 169-184. SID. https://sid.ir/paper/405766/en

    Vancouver: Copy

    SHEKARI A., SAFAVI S.E., MOUSAVI GH.. Effect of Coenzyme Q10 on testicular tissue after correction of experimental cryptorchidism in rat. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ)[Internet]. 2020;14(2 (54) ):169-184. Available from: https://sid.ir/paper/405766/en

    IEEE: Copy

    A. SHEKARI, S.E. SAFAVI, and GH. MOUSAVI, “Effect of Coenzyme Q10 on testicular tissue after correction of experimental cryptorchidism in rat,” VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), vol. 14, no. 2 (54) , pp. 169–184, 2020, [Online]. Available: https://sid.ir/paper/405766/en

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