The protective effect of alcoholic extract of Allium cepa seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Kamani Mehran; NIKZAD HOSSEIN; KHODADADI MARYAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE) Year:2020 | Volume:5 | Issue:3 Page(s): 134-141

Download Full-Text

Persian Verion

View:

173

Download:

Cites:

Information Journal Paper

Title

The protective effect of alcoholic extract of Allium cepa seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats

Author(s)

Kamani Mehran | NIKZAD HOSSEIN | KHODADADI MARYAM | Issue Writer Certificate

Keywords

Diabetes

Epididymis

Onion seed extract

Streptozotocine

Insulin

Abstract

Aims: Diabetes has adverse effect on male reproductive system. The onion (Allium cepa) seed is a rich natural source of antioxidant which can improve the damaging effects caused by Diabetes on different tissues. The aim of this study was to examine the effect of alcoholic extract of onion seeds on the histopathological changes of Epididymis in Streptozotocine-induced diabetic rats. Methods: In this experimental study, 50 adult male Wistar rats were allocated into 5 groups (n=10). Groups 1 and 2 received 0. 1 CC ethanol extract of onion seed in dosages of 200 and 400 mg/ kg body weight (B. W. ) by stomach gavage daily. Group 3 (as control group) included healthy rats that received normal water and food for 4 weeks. Group 4 included untreated diabetic rats that received an intraperitoneal injection of STZ 60 mg/kg B. W. and with FBS>250 mg/ dose 3U/100 g B. W. by subcutaneous injection. Histological and morphological structures of the Epididymis was evaluated in different groups. Findings: Our data showed that the histology parameters in diabetic rats receiving the extract was improved significantly. Administration of both doses of 200 and 400 mg/kg B. W. Onion seed extract could increase epithelium height and decrease fibromuscular thickness significantly. Also, data demonstrated that tubule and lumen diameter did not change significantly in onion extract-treated groups. Conclusion: Our finding indicated that Onion seed extract may be useful as a supplementary protective agent against adverse effects of Diabetes on reproductive system in diabetic men.

Cites

No record.

References

No record.

Cite

APA: Copy

Kamani, Mehran, NIKZAD, HOSSEIN, & KHODADADI, MARYAM. (2020). The protective effect of alcoholic extract of Allium cepa seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), 5(3 ), 134-141. SID. https://sid.ir/paper/410969/en

Vancouver: Copy

Kamani Mehran, NIKZAD HOSSEIN, KHODADADI MARYAM. The protective effect of alcoholic extract of Allium cepa seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2020;5(3 ):134-141. Available from: https://sid.ir/paper/410969/en

IEEE: Copy

Mehran Kamani, HOSSEIN NIKZAD, and MARYAM KHODADADI, “The protective effect of alcoholic extract of Allium cepa seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats,” SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), vol. 5, no. 3 , pp. 134–141, 2020, [Online]. Available: https://sid.ir/paper/410969/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops