Investigation Effects of Phosphate Salt in the Extraction of Malic Acid Using Aqueous Two-Phase Systems

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masoomi hadiseh; Ghannadzadeh Gilani Hossein

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Journal Paper

Paper Information

Journal: Nashrieh Shimi va Mohandesi Shimi Iran Year:2021 | Volume:39 | Issue:4 (98) Page(s): 167-175

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Information Journal Paper

Title

Investigation Effects of Phosphate Salt in the Extraction of Malic Acid Using Aqueous Two-Phase Systems

Author(s)

masoomi hadiseh | Ghannadzadeh Gilani Hossein | Issue Writer Certificate

Keywords

Malic acidQ1

partition coefficientQ1

Percentage of extractionQ1

Aqueous two-phase systemQ1

Polyethylene glycolQ1

Phosphate saltQ1

Abstract

Novel separation methods that are necessary for the purification of biomolecules and carboxylic acids at industries, are expanding. Therefore, these methods should be fast, selective, and easy to scale up. The Aqueous two-phase system is an effective separation procedure for the purification of materials. The purification of biomolecules and carboxylic acids is extremely selective by this method and also, the separation process is conducted in one step. This research aimed to investigate the effects of molecular weight of Polyethylene glycol, pH, salt concentration, and salt type in polymer/salt Aqueous two-phase systems. In this research, purification of Malic acid in Aqueous two-phase systems containing Polyethylene glycol 4000 and 8000 g/mol, different concentration sodium di hydrogen phosphate, diammonium hydrogen phosphate, and di potassium hydrogen phosphate were studied. After investigating the effective factors, the best operation conditions for Malic acid extraction was obtained in a system composed of PEG4000, 0. 25 (w/w) sodium di hydrogen phosphate at pH=5. The purification parameters such as partition coefficient of Malic acid and yield were achieved 0. 85 and 80%, respectively.

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APA: Copy

masoomi, hadiseh, & Ghannadzadeh Gilani, Hossein. (2021). Investigation Effects of Phosphate Salt in the Extraction of Malic Acid Using Aqueous Two-Phase Systems. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), 39(4 (98) ), 167-175. SID. https://sid.ir/paper/411785/en

Vancouver: Copy

masoomi hadiseh, Ghannadzadeh Gilani Hossein. Investigation Effects of Phosphate Salt in the Extraction of Malic Acid Using Aqueous Two-Phase Systems. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN)[Internet]. 2021;39(4 (98) ):167-175. Available from: https://sid.ir/paper/411785/en

IEEE: Copy

hadiseh masoomi, and Hossein Ghannadzadeh Gilani, “Investigation Effects of Phosphate Salt in the Extraction of Malic Acid Using Aqueous Two-Phase Systems,” NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), vol. 39, no. 4 (98) , pp. 167–175, 2021, [Online]. Available: https://sid.ir/paper/411785/en

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