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Information Journal Paper

Title

Effect of Eight Weeks Aerobic Training on The Levels of Antioxidant Enzymes in The Heart Tissue of Type 2 Diabetic Rats

Pages

  49-60

Abstract

 Inroduction & Objective: Chronic hyperglycemia is associated with enhanced oxidative stress-induced myocardial injury. The aim of this study was to investigate the of eight weeks Aerobic Training on the levels of Antioxidant Enzymes in the Heart Tissue of type 2 diabetic Rats. Material and Methods: To implementation of this experimental research, 40 male Wistar Rats (weight 185. 2± 22. 7 gr) randomly were divided into 4 groups including control, Diabetes, training and Diabetes-training. In this study, the Rats were type 2 diabetic using peritoneal injection nicotinamide-STZ. Aerobic Training performed with intensity of 50-60% VO2max, 5 days a week and for 8 weeks. The levels of the antioxidant catalase, superoxide dismutase and glutathione peroxidase in Heart Tissue were measured using kit and by ELISA method. Data were analyzed by One-way ANOVA and Tukey post hoc test at the P<0. 05. Results: The results showed that the levels of Antioxidant Enzymes (catalase, superoxide dismutase and glutathione peroxidase) in the Heart Tissue of type 2 diabetic control Rats was lower than the healthy control group (P=0. 001). Eight weeks of Aerobic Training significantly increased the levels of Antioxidant Enzymes (catalase, superoxide dismutase and glutathione peroxidase) in the Heart Tissue of type 2 diabetic Rats (P=0. 001). Conclusion: According to the research results, aerobic exercise may improve the cardiac function of diabetic subjects by increasing the Antioxidant Enzymes in the Heart Tissue. As a result, these training are recommended as adjunctive therapy in these patients.

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    APA: Copy

    REZAEI, S., Abbassi Daloi, A., BARARI, A.R., & AHMADI, M.. (2020). Effect of Eight Weeks Aerobic Training on The Levels of Antioxidant Enzymes in The Heart Tissue of Type 2 Diabetic Rats. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), 13(4 (51) ), 49-60. SID. https://sid.ir/paper/411816/en

    Vancouver: Copy

    REZAEI S., Abbassi Daloi A., BARARI A.R., AHMADI M.. Effect of Eight Weeks Aerobic Training on The Levels of Antioxidant Enzymes in The Heart Tissue of Type 2 Diabetic Rats. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES)[Internet]. 2020;13(4 (51) ):49-60. Available from: https://sid.ir/paper/411816/en

    IEEE: Copy

    S. REZAEI, A. Abbassi Daloi, A.R. BARARI, and M. AHMADI, “Effect of Eight Weeks Aerobic Training on The Levels of Antioxidant Enzymes in The Heart Tissue of Type 2 Diabetic Rats,” JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), vol. 13, no. 4 (51) , pp. 49–60, 2020, [Online]. Available: https://sid.ir/paper/411816/en

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