PREPARATION OF CHITOSAN DERIVED FROM SHRIMP

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MIRZADEH HAMID; YAGHOUBI N.; AMANPOUR S.; AHMADI HOSSEIN; MOHAGHEGHI S.M.A.; HORMOZI F.

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Journal Paper

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Journal: Iranian Polymer Journal Year:2002 | Volume:11 | Issue:1 Page(s): 63-68

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Title

PREPARATION OF CHITOSAN DERIVED FROM SHRIMP"S SHELL OF PERSIAN GULF AS A BLOOD HEMOSTASIS AGENT

Author(s)

Keywords

CHITOSAN

HEMOSTASIS

IN VIVO

CAROTID ARTERY

CHITIN

Abstract

In this study CHITIN was extracted from shrimp's shell of Persian Gulf, using different methods and CHITOSAN is derived from CHITIN as a microcrystalline powder, which is being named as Persian Gulf CHITOSAN (PGC) with deacetylation degree of 86 % and the viscosity-average molecular weight (M v) of 3.57x105. The purpose of this experiment was to evaluate the effectiveness and safety of PGC as a HEMOSTASIS agent with surgical application. Results using PGC in sheep carotid punctured hole model showed significant reduction in manual compression time (p<0.009) of the CAROTID ARTERY. Comparative results were found in sheep, wherein a created wound in the CAROTID ARTERY could be sealed relatively quickly and easily. There were no significant differences in time length to HEMOSTASIS between heparinized and non-heparinized sheep. This work suggests that PGC is a safe and effective biopolymer to achieve HEMOSTASIS.

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APA: Copy

MIRZADEH, HAMID, YAGHOUBI, N., AMANPOUR, S., AHMADI, HOSSEIN, MOHAGHEGHI, S.M.A., & HORMOZI, F.. (2002). PREPARATION OF CHITOSAN DERIVED FROM SHRIMP"S SHELL OF PERSIAN GULF AS A BLOOD HEMOSTASIS AGENT . IRANIAN POLYMER JOURNAL (ENGLISH), 11(1), 63-68. SID. https://sid.ir/paper/528370/en

Vancouver: Copy

MIRZADEH HAMID, YAGHOUBI N., AMANPOUR S., AHMADI HOSSEIN, MOHAGHEGHI S.M.A., HORMOZI F.. PREPARATION OF CHITOSAN DERIVED FROM SHRIMP"S SHELL OF PERSIAN GULF AS A BLOOD HEMOSTASIS AGENT . IRANIAN POLYMER JOURNAL (ENGLISH)[Internet]. 2002;11(1):63-68. Available from: https://sid.ir/paper/528370/en

IEEE: Copy

HAMID MIRZADEH, N. YAGHOUBI, S. AMANPOUR, HOSSEIN AHMADI, S.M.A. MOHAGHEGHI, and F. HORMOZI, “PREPARATION OF CHITOSAN DERIVED FROM SHRIMP"S SHELL OF PERSIAN GULF AS A BLOOD HEMOSTASIS AGENT ,” IRANIAN POLYMER JOURNAL (ENGLISH), vol. 11, no. 1, pp. 63–68, 2002, [Online]. Available: https://sid.ir/paper/528370/en

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