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Information Journal Paper

Title

ENANTIOSELECTIVE EXTRACTION OF OFLOXACIN ENANTIOMERS USING ESTER ALCOHOL L-TARTARATE AS CHIRAL SELECTOR

Pages

  7-11

Abstract

 The distribution behavior of OFLOXACIN ENANTIOMERS was examined in the aqueous and organic solvent of a two-phase system containing chiral selector L-TARTARATE. The effect of extraction equilibrium time, buffer pH, organic solvents and length of alkyl chain of L-TARTARATE on the PARTITION COEFFICIENTs and ENANTIOSELECTIVITY of racemic ofloxacin were investigated, respectively. The L-TARTARATE formed more stable complexes with R-ofloxacin than that with S-ofloxacin. The PARTITION COEFFICIENTs and ENANTIOSELECTIVITY of racemic ofloxacin increased with increasing length of alkyl chain of L-TARTARATE. Solvents showed a large influence on ENANTIOSELECTIVITY and PARTITION COEFFICIENTs. Optimum buffer pH was about 7 for separation of racemic ofloxacin by extraction.

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    • Cite

    APA: Copy

    FEIPENG, J., XIAOQING, CH., & XINYU, J.. (2009). ENANTIOSELECTIVE EXTRACTION OF OFLOXACIN ENANTIOMERS USING ESTER ALCOHOL L-TARTARATE AS CHIRAL SELECTOR. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), 28(1), 7-11. SID. https://sid.ir/paper/546551/en

    Vancouver: Copy

    FEIPENG J., XIAOQING CH., XINYU J.. ENANTIOSELECTIVE EXTRACTION OF OFLOXACIN ENANTIOMERS USING ESTER ALCOHOL L-TARTARATE AS CHIRAL SELECTOR. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE)[Internet]. 2009;28(1):7-11. Available from: https://sid.ir/paper/546551/en

    IEEE: Copy

    J. FEIPENG, CH. XIAOQING, and J. XINYU, “ENANTIOSELECTIVE EXTRACTION OF OFLOXACIN ENANTIOMERS USING ESTER ALCOHOL L-TARTARATE AS CHIRAL SELECTOR,” IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), vol. 28, no. 1, pp. 7–11, 2009, [Online]. Available: https://sid.ir/paper/546551/en

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