COMPATIBILITY STUDY OF ASPARTAME AND DRUGS USING DIFFERENTIAL SCANNING CALORIMETRY (DSC)

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GHRAVI S.M.; TAVAKOLI N.

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Paper Information

Journal: RESEARCH JOURNAL OF UNIVERSITY OF ISFAHAN "SCIENCE" Year:2001 | Volume:14 | Issue:2 Page(s): 77-84

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Title

COMPATIBILITY STUDY OF ASPARTAME AND DRUGS USING DIFFERENTIAL SCANNING CALORIMETRY (DSC)

Author(s)

GHRAVI S.M. | TAVAKOLI N.

Keywords

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Abstract

For formulation of new products or reformulation of existing ones, it is wise to know possibility of any interaction of drug-drug or drug additive, which will affect the stability of final product.In this study, first thermograms of aspartame and each drug were prepared individually, then thermograms of an equal mixture of drug and aspartame was drug prepared and compared with the pure and aspartame thermograms.DSC thermograms of chloropheniramine and phenylephrine showed a deformation and shift in the peak indicating probable interaction while acetminophen and sulphamethoxazole had no changes in their thermograms, therefore no interaction between aspartame and those drugs can exist.

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APA: Copy

GHRAVI, S.M., & TAVAKOLI, N.. (2001). COMPATIBILITY STUDY OF ASPARTAME AND DRUGS USING DIFFERENTIAL SCANNING CALORIMETRY (DSC). RESEARCH JOURNAL OF UNIVERSITY OF ISFAHAN "SCIENCE", 14(2), 77-84. SID. https://sid.ir/paper/55807/en

Vancouver: Copy

GHRAVI S.M., TAVAKOLI N.. COMPATIBILITY STUDY OF ASPARTAME AND DRUGS USING DIFFERENTIAL SCANNING CALORIMETRY (DSC). RESEARCH JOURNAL OF UNIVERSITY OF ISFAHAN "SCIENCE"[Internet]. 2001;14(2):77-84. Available from: https://sid.ir/paper/55807/en

IEEE: Copy

S.M. GHRAVI, and N. TAVAKOLI, “COMPATIBILITY STUDY OF ASPARTAME AND DRUGS USING DIFFERENTIAL SCANNING CALORIMETRY (DSC),” RESEARCH JOURNAL OF UNIVERSITY OF ISFAHAN "SCIENCE", vol. 14, no. 2, pp. 77–84, 2001, [Online]. Available: https://sid.ir/paper/55807/en

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