PREPARATION AND RELEASE BEHAVIOR EVALUATION OF H9N2 AVIAN INFLUENZA VIRUS LOADED PLGA MICROSPHERES USING DOUBLE EMULSION-SOLVENT EVAPORATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHAZEI J.; OURANG F.; NAZARI SHIRVAN A.; AMINIAN M.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: AMIRKABIR Year:2008 | Volume:18 | Issue:67-A (TOPICS IN: GROUPS OF ENGINEERING, ELECTRONIC, BIOMEDICAL, COMPUTER) Page(s): 59-68

Download Full-Text

View:

254

Download:

Cites:

Information Journal Paper

Title

PREPARATION AND RELEASE BEHAVIOR EVALUATION OF H9N2 AVIAN INFLUENZA VIRUS LOADED PLGA MICROSPHERES USING DOUBLE EMULSION-SOLVENT EVAPORATION

Author(s)

KHAZEI J. | OURANG F. | NAZARI SHIRVAN A. | AMINIAN M. | Issue Writer Certificate

Keywords

CONTROLLED RELEASE DRUG DELIVERY SYSTEMS

BIODEGRADABLE POLYMERS

DOUBLE EMULSION-SOLVENT EVAPORATION METHOD

MICROSPHERE

POLY (LACTIC-CO-GLYCOLIC ACID)

AVIAN INFLUENZA VIRUS (H9N2)

Abstract

Microparticulate form of BIODEGRADABLE POLYMERS containing drugs is a promising approach toward new CONTROLLED RELEASE DRUG DELIVERY SYSTEMS, and a perfect alternative for daily painful injection of protein drugs. One major challenge in developing such systems is increasing efficiency of fabrication processes and retaining stability and effectiveness of encapsulated proteins and drugs. In this study capabilities of double emulsion (W/O/W)-solvent evaporation method for encapsulation of attenuated avian influenza virus (H9N2) in poly (lactic-co-glycolic acid) 50:50 were investigated and, the protein in vitro release profiles were determined. Some basic salts such as MgCO3 co-encapsulated with protein were used to increase stability and release of the protein. Additives such as NaCL and urea were added to second water phase to ensure and increase loading of the protein. The MICROSPHEREs were all spherical with almost smooth surface and some small pores. Release profiles reveal that MgCO3 increased the amount of released protein but did not have a significant effect on release rate.

Cites

No record.

References

No record.

Cite

APA: Copy

KHAZEI, J., OURANG, F., NAZARI SHIRVAN, A., & AMINIAN, M.. (2008). PREPARATION AND RELEASE BEHAVIOR EVALUATION OF H9N2 AVIAN INFLUENZA VIRUS LOADED PLGA MICROSPHERES USING DOUBLE EMULSION-SOLVENT EVAPORATION. AMIRKABIR, 18(67-A (TOPICS IN: GROUPS OF ENGINEERING, ELECTRONIC, BIOMEDICAL, COMPUTER)), 59-68. SID. https://sid.ir/paper/574778/en

Vancouver: Copy

KHAZEI J., OURANG F., NAZARI SHIRVAN A., AMINIAN M.. PREPARATION AND RELEASE BEHAVIOR EVALUATION OF H9N2 AVIAN INFLUENZA VIRUS LOADED PLGA MICROSPHERES USING DOUBLE EMULSION-SOLVENT EVAPORATION. AMIRKABIR[Internet]. 2008;18(67-A (TOPICS IN: GROUPS OF ENGINEERING, ELECTRONIC, BIOMEDICAL, COMPUTER)):59-68. Available from: https://sid.ir/paper/574778/en

IEEE: Copy

J. KHAZEI, F. OURANG, A. NAZARI SHIRVAN, and M. AMINIAN, “PREPARATION AND RELEASE BEHAVIOR EVALUATION OF H9N2 AVIAN INFLUENZA VIRUS LOADED PLGA MICROSPHERES USING DOUBLE EMULSION-SOLVENT EVAPORATION,” AMIRKABIR, vol. 18, no. 67-A (TOPICS IN: GROUPS OF ENGINEERING, ELECTRONIC, BIOMEDICAL, COMPUTER), pp. 59–68, 2008, [Online]. Available: https://sid.ir/paper/574778/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops