مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

684
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

265
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

SIMULTANEOUS DETERMINATION OF HYDROCHLOROTHIAZIDE AND ENALAPRIL MALEATE IN PHARMACEUTICAL FORMULATIONS USING FOURIER TRANSFORM INFRARED SPECTROMETRY

Pages

  59-67

Abstract

 A new Fourier Transform-Infra Red (FT-IR) spectrometric method was developed for assaying HYDROCHLOROTHIAZIDE (HCT) and ENALAPRIL MALEATE (ENM) in binary solid PHARMACEUTICAL FORMULATIONs. Multivariate Partial Least Squares (PLS) method was used for calibration of derivative spectral data. Acetonitrile was used as solvent due to its spectral transparency and adequate solubility of analytes in it. A 4- levels full factorial design of binary standard solutions of HCT and ENM were prepared and used for calibration in the spectral range of 1550-1800 cm-1. Statistical parameters such as correlation coefficient (R), Standard Error of Estimation (SEE), Standard Error of Prediction (SEP), and Standard Error of Cross Validation (SECV) have been evaluated and used for selecting of optimizing of parameters. Correlation coefficients were 0.9990 and 0.9995 and Relative Standard Deviation (RSD) were 1.97% and 1.35% (n=5) for HCT and ENM, respectively. Detection limits of ENM and HCT were obtained 0.54 and 0.99 mg/mL respectively. The proposed methods were successfully applied to the determination of the over mentioned drugs in laboratory-prepared mixtures and in commercial tablets. This method has suitable accuracy, precision, repeatability and is comparable with reference standard methods.

Cites

References

Cite

APA: Copy

AHMADI, SEYYED HAMID, TAVAKOLI, HASSAN, AMIRZADEH, MAJID, & SANGI, MOHAMMAD REZA. (2014). SIMULTANEOUS DETERMINATION OF HYDROCHLOROTHIAZIDE AND ENALAPRIL MALEATE IN PHARMACEUTICAL FORMULATIONS USING FOURIER TRANSFORM INFRARED SPECTROMETRY. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), 33(4), 59-67. SID. https://sid.ir/paper/631244/en

Vancouver: Copy

AHMADI SEYYED HAMID, TAVAKOLI HASSAN, AMIRZADEH MAJID, SANGI MOHAMMAD REZA. SIMULTANEOUS DETERMINATION OF HYDROCHLOROTHIAZIDE AND ENALAPRIL MALEATE IN PHARMACEUTICAL FORMULATIONS USING FOURIER TRANSFORM INFRARED SPECTROMETRY. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE)[Internet]. 2014;33(4):59-67. Available from: https://sid.ir/paper/631244/en

IEEE: Copy

SEYYED HAMID AHMADI, HASSAN TAVAKOLI, MAJID AMIRZADEH, and MOHAMMAD REZA SANGI, “SIMULTANEOUS DETERMINATION OF HYDROCHLOROTHIAZIDE AND ENALAPRIL MALEATE IN PHARMACEUTICAL FORMULATIONS USING FOURIER TRANSFORM INFRARED SPECTROMETRY,” IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), vol. 33, no. 4, pp. 59–67, 2014, [Online]. Available: https://sid.ir/paper/631244/en

Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops





    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button