COMPARATIVE STUDY ON ERI SILK AND MULBERRY SILK FIBROIN SCAFFOLDS FOR BIOMEDICAL APPLICATIONS

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MUTHUMANICKKAM ANDIYAPPAN; SUNDARAMOORTHY SUBRAMANIAN; GOWERI MAHIZHAPPAN; WINFRED SOFI BEAULA; VENKATARAMAN GANESH

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Journal: Iranian Polymer Journal Year:2013 | Volume:22 | Issue:3 Page(s): 143-154

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Title

COMPARATIVE STUDY ON ERI SILK AND MULBERRY SILK FIBROIN SCAFFOLDS FOR BIOMEDICAL APPLICATIONS

Author(s)

Keywords

ERI SILK FIBROIN

MULBERRY SILK FIBROIN

TENSILE STRENGTH

BLOOD COMPATIBILITY

CELL ATTACHMENT

Abstract

Mulberry silk fibroin is being used as biomaterial for tissue engineering applications. In the present work, comparisons are made between mulberry and ERI SILK FIBROIN scaffolds prepared by electrospinning method. The scaffolds are treated with ethanol to improve their dimensional stability, and the physical and chemical properties of the scaffolds are assessed using thermogravimetric analyzer (TGA), differential scanning calorimetry, Fourier transform infrared spectroscopy and X-ray diffractometry. The FTIR spectra confirm the structural change of silk fibroin from α-helical to b-sheet structure when mulberry and eri silk scaffolds are treated with ethanol. The thermal stability of the eri silk scaffold is found to be better than that of mulberry silk. Ethanol-treated eri silk displays higher tensile stress than the ethanol-treated mulberry silk. The hemolysis percentages of eri silk and mulberry silk scaffolds are found to be 1 and 3 %, respectively. While the platelet adhesion on ERI SILK FIBROIN scaffold is found to be lower than that of MULBERRY SILK FIBROIN scaffold, the CELL ATTACHMENT, binding and spreading of L6 fibroblast cells on the eri silk scaffold are better than those on the MULBERRY SILK FIBROIN, and the cell viability is found to be better on ERI SILK FIBROIN scaffold.

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APA: Copy

MUTHUMANICKKAM, ANDIYAPPAN, SUNDARAMOORTHY, SUBRAMANIAN, GOWERI, MAHIZHAPPAN, WINFRED, SOFI BEAULA, & VENKATARAMAN, GANESH. (2013). COMPARATIVE STUDY ON ERI SILK AND MULBERRY SILK FIBROIN SCAFFOLDS FOR BIOMEDICAL APPLICATIONS. IRANIAN POLYMER JOURNAL (ENGLISH), 22(3), 143-154. SID. https://sid.ir/paper/635465/en

Vancouver: Copy

MUTHUMANICKKAM ANDIYAPPAN, SUNDARAMOORTHY SUBRAMANIAN, GOWERI MAHIZHAPPAN, WINFRED SOFI BEAULA, VENKATARAMAN GANESH. COMPARATIVE STUDY ON ERI SILK AND MULBERRY SILK FIBROIN SCAFFOLDS FOR BIOMEDICAL APPLICATIONS. IRANIAN POLYMER JOURNAL (ENGLISH)[Internet]. 2013;22(3):143-154. Available from: https://sid.ir/paper/635465/en

IEEE: Copy

ANDIYAPPAN MUTHUMANICKKAM, SUBRAMANIAN SUNDARAMOORTHY, MAHIZHAPPAN GOWERI, SOFI BEAULA WINFRED, and GANESH VENKATARAMAN, “COMPARATIVE STUDY ON ERI SILK AND MULBERRY SILK FIBROIN SCAFFOLDS FOR BIOMEDICAL APPLICATIONS,” IRANIAN POLYMER JOURNAL (ENGLISH), vol. 22, no. 3, pp. 143–154, 2013, [Online]. Available: https://sid.ir/paper/635465/en

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