OPTIMIZATION OF ATROPINE EXTRACTION PROCESS FROM ATROPA BELLADONNA BY MODIFIED BUBBLE COLUMN EXTRACTOR WITH ULTRASONIC BATH

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Abbaspour Akbar; Khadiv Parsi Parissa; KHALIGHI SIGAROODI FARAHNAZ; Ghafarzadegan Reza

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Journal Paper

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Journal: Iranian Journal of Chemistry and Chemical Engineering Year:2016 | Volume:35 | Issue:4 Page(s): 49-60

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Title

OPTIMIZATION OF ATROPINE EXTRACTION PROCESS FROM ATROPA BELLADONNA BY MODIFIED BUBBLE COLUMN EXTRACTOR WITH ULTRASONIC BATH

Author(s)

Abbaspour Akbar | Khadiv Parsi Parissa | KHALIGHI SIGAROODI FARAHNAZ | Ghafarzadegan Reza | Issue Writer Certificate

Keywords

ATROPINE

BUBBLE COLUMN EXTRACTION

UNIFORM DESIGN

UV-VISIBLE SPECTROSCOPY

ATROPA BELLADONNA

Abstract

Modified BUBBLE COLUMN EXTRACTION with Ultrasonic Bath (BCE-UB) method was used to extract ATROPINE from the stem and leaves of ATROPA BELLADONNA. Optimum condition were obtained with Kamada solvent which was chloroform-methanol-ammonia 15: 15: 1 (v/v/v) as extraction solvent, the particle size of less than 350 mm, an extraction time of 23.95 min, a liquor to material ratio of 15.08 mL/g and an air flow of 6.31 mL/min.g. In this state, percent of extracted ATROPINE was calculated which was equal to 6.81%. Percent of extracted ATROPINE was 6.31% that showed a little difference compared to the predicted value. In order to study the effect of bubbles on the extraction rate, the same extraction with the previous method was performed in a stirred tank. Percent of ATROPINE was 5.59%.

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APA: Copy

Abbaspour, Akbar, Khadiv Parsi, Parissa, KHALIGHI SIGAROODI, FARAHNAZ, & Ghafarzadegan, Reza. (2016). OPTIMIZATION OF ATROPINE EXTRACTION PROCESS FROM ATROPA BELLADONNA BY MODIFIED BUBBLE COLUMN EXTRACTOR WITH ULTRASONIC BATH. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), 35(4), 49-60. SID. https://sid.ir/paper/682330/en

Vancouver: Copy

Abbaspour Akbar, Khadiv Parsi Parissa, KHALIGHI SIGAROODI FARAHNAZ, Ghafarzadegan Reza. OPTIMIZATION OF ATROPINE EXTRACTION PROCESS FROM ATROPA BELLADONNA BY MODIFIED BUBBLE COLUMN EXTRACTOR WITH ULTRASONIC BATH. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE)[Internet]. 2016;35(4):49-60. Available from: https://sid.ir/paper/682330/en

IEEE: Copy

Akbar Abbaspour, Parissa Khadiv Parsi, FARAHNAZ KHALIGHI SIGAROODI, and Reza Ghafarzadegan, “OPTIMIZATION OF ATROPINE EXTRACTION PROCESS FROM ATROPA BELLADONNA BY MODIFIED BUBBLE COLUMN EXTRACTOR WITH ULTRASONIC BATH,” IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), vol. 35, no. 4, pp. 49–60, 2016, [Online]. Available: https://sid.ir/paper/682330/en

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