SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL SCREENING OF THE XANTHATE DERIVATIVES AND THEIR IRON(II) COMPLEXES

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MANSOURI TORSHIZI HASSAN; ZAREIAN JAHROMI SAREH; SAEIDIFAR MARYAM; GHASEMI ALI; GHAEMI HAMED; HEYDARI ALI

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Journal: Iranian Journal of Chemistry and Chemical Engineering Year:2017 | Volume:36 | Issue:5 Page(s): 43-54

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Title

SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL SCREENING OF THE XANTHATE DERIVATIVES AND THEIR IRON(II) COMPLEXES

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Keywords

XANTHATE

FE(II) COMPLEX

ANTIFUNGAL ACTIVITY

ANTIBACTERIAL ACTIVITY

Abstract

Seven reported XANTHATE ligands and their new Fe (II) complexes of formulaNa [Fe (R-OCSS)3], where R is ethyl-, propyl-, butyl-, pentyl-, Hexyl-, heptyl- and octyl-XANTHATE have been synthesized.They have been characterized using elemental analysis, molar conductance, FT-IR, UV-Vis and 1H NMR spectroscopic techniques and melting-, decomposition-points for ligands and complexes respectively. All the ligands and their Fe (II) complexes have been evaluated for their antimicrobial activity against four gram-positive bacteria, four gram-negative bacteria and three fungi by agar disc diffusion technique. The MIC values of the compounds exhibited significant ANTIFUNGAL ACTIVITY but showed lower ANTIBACTERIAL ACTIVITY. The iron (II) complexes are found to possess higher antimicrobial activity than their counterpart ligands thus improving its antimicrobial efficacy.Hydrocarbon chain length of the ligands coordinated to Fe (II) centers seemed to be important for their antifungal as well as antibacterial activities.

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APA: Copy

MANSOURI TORSHIZI, HASSAN, ZAREIAN JAHROMI, SAREH, SAEIDIFAR, MARYAM, GHASEMI, ALI, GHAEMI, HAMED, & HEYDARI, ALI. (2017). SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL SCREENING OF THE XANTHATE DERIVATIVES AND THEIR IRON(II) COMPLEXES. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), 36(5), 43-54. SID. https://sid.ir/paper/708814/en

Vancouver: Copy

MANSOURI TORSHIZI HASSAN, ZAREIAN JAHROMI SAREH, SAEIDIFAR MARYAM, GHASEMI ALI, GHAEMI HAMED, HEYDARI ALI. SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL SCREENING OF THE XANTHATE DERIVATIVES AND THEIR IRON(II) COMPLEXES. IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE)[Internet]. 2017;36(5):43-54. Available from: https://sid.ir/paper/708814/en

IEEE: Copy

HASSAN MANSOURI TORSHIZI, SAREH ZAREIAN JAHROMI, MARYAM SAEIDIFAR, ALI GHASEMI, HAMED GHAEMI, and ALI HEYDARI, “SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL SCREENING OF THE XANTHATE DERIVATIVES AND THEIR IRON(II) COMPLEXES,” IRANIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING (IJCCE), vol. 36, no. 5, pp. 43–54, 2017, [Online]. Available: https://sid.ir/paper/708814/en

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