SYNTHESIS AND ANTI CANCER ACTIVITY OF PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES

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KUMAR V.; SANNA V.K.; SINGH A.T.; JAGGI M.; SHARMA P.K.; IRCHHAIYA R.; BURMAN A.C.

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Journal: Journal of Sciences, Islamic Republic of Iran Year:2009 | Volume:20 | Issue:4 Page(s): 325-329

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Title

SYNTHESIS AND ANTI CANCER ACTIVITY OF PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES

Author(s)

Keywords

PYRIDO[2Q3

3-C]PYRIDAZINEQ3

ANTI CANCERQ3

CYTOTOXICQ3

Abstract

Cancer is not just one disease, but a large group of almost one hundred diseases. Its two main characteristics are uncontrolled growth of the cells in the human body and the ability of these cells to migrate from the original site and spread to distant sites. If the spread is not controlled, cancer can result in death.There has been continuous progress in the development of therapy for cancer. The successful treatment of cancer still remains a challenge. A new series of pyrido[2,3-c]pyridazine derivatives (8-14) were synthesized and screened for their anticancer activity. Amongst them few of the compounds have exhibited promising cytotoxicity along with good safety index. These compounds could be of use in designing new anti-cancer agents.

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APA: Copy

KUMAR, V., SANNA, V.K., SINGH, A.T., JAGGI, M., SHARMA, P.K., IRCHHAIYA, R., & BURMAN, A.C.. (2009). SYNTHESIS AND ANTI CANCER ACTIVITY OF PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES. JOURNAL OF SCIENCES ISLAMIC REPUBLIC OF IRAN, 20(4), 325-329. SID. https://sid.ir/paper/84144/en

Vancouver: Copy

KUMAR V., SANNA V.K., SINGH A.T., JAGGI M., SHARMA P.K., IRCHHAIYA R., BURMAN A.C.. SYNTHESIS AND ANTI CANCER ACTIVITY OF PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES. JOURNAL OF SCIENCES ISLAMIC REPUBLIC OF IRAN[Internet]. 2009;20(4):325-329. Available from: https://sid.ir/paper/84144/en

IEEE: Copy

V. KUMAR, V.K. SANNA, A.T. SINGH, M. JAGGI, P.K. SHARMA, R. IRCHHAIYA, and A.C. BURMAN, “SYNTHESIS AND ANTI CANCER ACTIVITY OF PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES,” JOURNAL OF SCIENCES ISLAMIC REPUBLIC OF IRAN, vol. 20, no. 4, pp. 325–329, 2009, [Online]. Available: https://sid.ir/paper/84144/en

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