KINETIC DISPOSITION, URINARY EXCRETION AND DOSAGE REGIMEN OF SUBCUTANEOUSLY ADMINISTERED LEVOFLOXACIN IN CROSS BRED CALVES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DUMKA V.K.; SRIVASTAVA A.K.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR) Year:2007 | Volume:8 | Issue:4 (21) Page(s): 313-318

Download Full-Text

Persian Verion

View:

11,278

Download:

189

Cites:

Information Journal Paper

Title

KINETIC DISPOSITION, URINARY EXCRETION AND DOSAGE REGIMEN OF SUBCUTANEOUSLY ADMINISTERED LEVOFLOXACIN IN CROSS BRED CALVES

Author(s)

DUMKA V.K. | SRIVASTAVA A.K. | Issue Writer Certificate

Keywords

CALVESQ3

DOSAGEQ3

LEVOFLOXACINQ3

SUBCUTANEOUSQ3

URINARY EXCRETIONQ3

Abstract

The present study was conducted on five healthy male cross bred CALVES to study the kinetic disposition and URINARY EXCRETION of LEVOFLOXACIN following its single SUBCUTANEOUS administration at the dose of 4 mg.kg-1. The concentration of LEVOFLOXACIN in plasma and urine samples was estimated by microbiological assay. Peak plasma level of LEVOFLOXACIN (2.8 ± 0.3 mg.ml-1) was observed at 45 min and the drug level above MIC90 in plasma, was detected up to 12 hrs of administration. The bioavailability of LEVOFLOXACIN was 41.9 ± 3.2%. High value of AUC (9.88 ± 0.1 mg.ml-1.hr) reflected a vast area of body covered by drug concentration. Good distribution of the drug was reflected by the high value of Vdarea (0.73 ± 0.04 L.kg-1). The elimination half-life and MRT were 3.0 ± 0.2 hr and 4.79 ± 0.2 hr, respectively. A suitable SUBCUTANEOUS DOSAGE regimen for LEVOFLOXACIN was calculated to be 1.25 mg.kg-1 repeated at 12-hr intervals in CALVES.

Cites

No record.

References

No record.

Cite

APA: Copy

DUMKA, V.K., & SRIVASTAVA, A.K.. (2007). KINETIC DISPOSITION, URINARY EXCRETION AND DOSAGE REGIMEN OF SUBCUTANEOUSLY ADMINISTERED LEVOFLOXACIN IN CROSS BRED CALVES. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), 8(4 (21)), 313-318. SID. https://sid.ir/paper/85568/en

Vancouver: Copy

DUMKA V.K., SRIVASTAVA A.K.. KINETIC DISPOSITION, URINARY EXCRETION AND DOSAGE REGIMEN OF SUBCUTANEOUSLY ADMINISTERED LEVOFLOXACIN IN CROSS BRED CALVES. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR)[Internet]. 2007;8(4 (21)):313-318. Available from: https://sid.ir/paper/85568/en

IEEE: Copy

V.K. DUMKA, and A.K. SRIVASTAVA, “KINETIC DISPOSITION, URINARY EXCRETION AND DOSAGE REGIMEN OF SUBCUTANEOUSLY ADMINISTERED LEVOFLOXACIN IN CROSS BRED CALVES,” IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), vol. 8, no. 4 (21), pp. 313–318, 2007, [Online]. Available: https://sid.ir/paper/85568/en

Related Journal Papers