ANGIOEDEMA FOLLOWING ORAL FINASTERIDE

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AGHAEI SARA; NABAVI MOHAMMAD; POURPAK Z.

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Seminar Paper

Paper Information

Seminar: BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY
Year:2007 | Issue:6

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Title

ANGIOEDEMA FOLLOWING ORAL FINASTERIDE

Author(s)

AGHAEI SARA | NABAVI MOHAMMAD | POURPAK Z.

Keywords

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Abstract

INTRODUCTION: Angioedema is caused by pathologic alterations that occur in the deep dermis and subcutaneous tissue and presents with swelling as the prominent manifestation and the appearance of the skin itself may be normal. The lesions have little or no associated pruritis, and the swelling may be described as painful or burning in nature. Many prescribed drugs can cause it as an adverse effect which in severe forms can be life-threatening. In this report a case of angioedema following the intake of a drug is described.CASE REPORT: This is a case report of a 74-year-old male who was started on Finasteride because of benign prostatic hyperplasia; 2 days later, he presented with perioral swelling. He had no past history of angioedema. He was examined for C1 Inhibitor protein that quantitative level was 639 and functional evaluation was normal.DISCUSSION: Finasteride is a competitive inhibitor of 5 alpha- reductase enzyme, and is used for treatment of benign prostatic hyperplasia and androgenetic alopecia; further evaluation is needed to determine whether angioedema should be added to the list of adverse events associated with finasteride.The recognition of drugs inducing angioedema constitutes a challenge to physicians to be cautious about prescribing such drugs for sensitive patients. Appropriate selection of drugs can prevent severe complications and can be life-saving.

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APA: Copy

AGHAEI, SARA, NABAVI, MOHAMMAD, & POURPAK, Z.. (2007). ANGIOEDEMA FOLLOWING ORAL FINASTERIDE. BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY. SID. https://sid.ir/paper/902530/en

Vancouver: Copy

AGHAEI SARA, NABAVI MOHAMMAD, POURPAK Z.. ANGIOEDEMA FOLLOWING ORAL FINASTERIDE. 2007. Available from: https://sid.ir/paper/902530/en

IEEE: Copy

SARA AGHAEI, MOHAMMAD NABAVI, and Z. POURPAK, “ANGIOEDEMA FOLLOWING ORAL FINASTERIDE,” presented at the BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY. 2007, [Online]. Available: https://sid.ir/paper/902530/en

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