AN EXPERIMENTAL ALLERGIC MODEL BY COMPLETE EXTRACT OF CUCUMIS MELO

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BODOUHI S.; KAMALINEZHAD MOHAMMAD; AMINI D.; AMANI D.; MOSAFA NARIMAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Seminar Paper

Paper Information

Seminar: BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY
Year:2007 | Issue:6

Download Full-Text

View:

204

Download:

Information Seminar Paper

Title

AN EXPERIMENTAL ALLERGIC MODEL BY COMPLETE EXTRACT OF CUCUMIS MELO

Author(s)

BODOUHI S. | KAMALINEZHAD MOHAMMAD | AMINI D. | AMANI D. | MOSAFA NARIMAN

Keywords

Not Registered.

Abstract

Objective: One of the major sources of allergic components is fruit. Modern Aechniue and methods has been tried to separate those for diagnostic approach to allergy clinics and also for established experimental allergic models in laboratory and therapeutics goals. Extract of cucumis melo consist “cucumisin” which is a very potent allergen. We decided to use total extracts of cucumis melo for experimental animal model of allergy.Material and Methods: 3 groups of animals (6 Inbred Balb/c mice) were used for this experimental study. The animals administered orally by complete extract of fruit mixed in drink water for 12 hours daily (according to appropriate).Concentration: (1/2, 1/4, 1/8). After 2 weeks with appearance of erythema and pruitus in skin, the animals were scarified with euthanasi technique and then we prepared blood samples for peripheral evaluation of basophilli and serum IgE level measurement. Excise some pieces of duodenum and skin sample for histological determination of tissue eosinophils and basophils and pathological studies Result: we detected great systemic basophile in all of the samples (up to 15%) in blood circulation. Another definds will be present in congress time.Discussions and conclusion: Appearance of systemic and sever basophilli leads us to establish and induction of an experimental allergic model for pharmacological study in allergy. If we can prove the increased serum level of IgE and measurement of skin/intestinal mucosal basophil and audiophile, we deduce and will be successful in our study. Purification and isolation of crude extract to 14, 36, 54 and 67 KD of cucumisin leads us to a more specific Allergic and Experimental model in laboratory investigations.

Cites

No record.

References

No record.

Cite

APA: Copy

BODOUHI, S., KAMALINEZHAD, MOHAMMAD, AMINI, D., AMANI, D., & MOSAFA, NARIMAN. (2007). AN EXPERIMENTAL ALLERGIC MODEL BY COMPLETE EXTRACT OF CUCUMIS MELO. BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY. SID. https://sid.ir/paper/902548/en

Vancouver: Copy

BODOUHI S., KAMALINEZHAD MOHAMMAD, AMINI D., AMANI D., MOSAFA NARIMAN. AN EXPERIMENTAL ALLERGIC MODEL BY COMPLETE EXTRACT OF CUCUMIS MELO. 2007. Available from: https://sid.ir/paper/902548/en

IEEE: Copy

S. BODOUHI, MOHAMMAD KAMALINEZHAD, D. AMINI, D. AMANI, and NARIMAN MOSAFA, “AN EXPERIMENTAL ALLERGIC MODEL BY COMPLETE EXTRACT OF CUCUMIS MELO,” presented at the BIENNIAL CONGRESS ON IMMUNOLOGY, ASTHMA AND ALLERGY. 2007, [Online]. Available: https://sid.ir/paper/902548/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops