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Information Seminar Paper

Title

RELATION BETWEEN REGULAR SWIMMING AND OXIDATIVE STRESS IN HIPPOCAMPUS OF DIABETIC MALE RATS

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Abstract

 Introduction: Diabetes is a metabolic disorder that produced by low secretion of insulin or resistant to insulin. Oxidative stress is an imbalance between the free radical production and antioxidant defense systems of the body and strongly related with diabetes and symptoms of it. Swimming exercise via enhancing antioxidant defenses can decrease the symptoms of diabetes.Methods: Diabetes was produced by streptozotocin (STZ, i.p injection, single dose, 50mg/Kg). Duration of exercise was 8 weeks. At the end of experiments, the rats were anesthetized by ether and the heads cut by guillotine, brain removed and hippocampus of brain was removed on ice immediately. Tissue was homogenized in prepared buffer and after sentrifusion produced supernatant was used for determination of SOD, GPX and CAT activities, and MDA level.Results: Diabetes reduced SOD activity and GPX of hippocampus in diabetic rats significantly. MDA level increased in diabetic rats significantly compared with control. In response to exercise MDA level decreased in diabetic rats and SOD activity, GPX and catalase activity increased significantly.Conclusion: Swimming exercise by increasing of hippocampus antioxidant enzymes and decreasing of MDA level has beneficial effects in prevention the neurotic symptoms of diabetes mellitus and tissue injuries by oxidative stress produced by this disease.

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    APA: Copy

    SALEHI, IRAJ, MOHAMMADI, MOSTAFA, FARAJNIA, S.A., & NAGINAGHADEH, A.. (2007). RELATION BETWEEN REGULAR SWIMMING AND OXIDATIVE STRESS IN HIPPOCAMPUS OF DIABETIC MALE RATS. IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. SID. https://sid.ir/paper/903124/en

    Vancouver: Copy

    SALEHI IRAJ, MOHAMMADI MOSTAFA, FARAJNIA S.A., NAGINAGHADEH A.. RELATION BETWEEN REGULAR SWIMMING AND OXIDATIVE STRESS IN HIPPOCAMPUS OF DIABETIC MALE RATS. 2007. Available from: https://sid.ir/paper/903124/en

    IEEE: Copy

    IRAJ SALEHI, MOSTAFA MOHAMMADI, S.A. FARAJNIA, and A. NAGINAGHADEH, “RELATION BETWEEN REGULAR SWIMMING AND OXIDATIVE STRESS IN HIPPOCAMPUS OF DIABETIC MALE RATS,” presented at the IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. 2007, [Online]. Available: https://sid.ir/paper/903124/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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