AN ECO- FRIENDLY ROUTE FOR SYNTHESIS OF FLUNIXIN MEGLUMINE

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HOSSEINI S.K.; BAGHERPOOR S.; YARHOSSEINI M.

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Seminar Paper

Paper Information

Seminar: SEMINAR OF CHEMISTRY AND ENVIRONMENT
Year:2015 | Issue:7

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Title

AN ECO- FRIENDLY ROUTE FOR SYNTHESIS OF FLUNIXIN MEGLUMINE

Author(s)

HOSSEINI S.K. | BAGHERPOOR S. | YARHOSSEINI M. | Issue Writer Certificate

Keywords

NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAID)

N-METHYL-D-GLUCAMINE

ENVIRONMENTALLY FRIENDLY REACTION CONDITIONS

Abstract

FLUNIXIN, KNOWN AS 2 [[2' -METHYL-3' - (TRIFLUOROMETHYL) PHENYL] AMINO] -3-PYRIDINE CARBOXYLIC ACID, IS A NON-STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID), ANALGESIC, AND ANTIPYRETIC USED IN VETERINARY MEDICINE. IT IS OFTEN FORMULATED AS THE MEGLUMINE SALT. THE ANALGESIC ACTIVITY OF N-METHYL- D -GLUCAMINE SALT OF FLUNIXIN (FLUNIXIN MEGLUMINE) IS COMPARABLE TO THAT OBSERVED BY POWERFUL NARCOTIC ANALGESICS SUCH AS MORPHINE, MEPERIDINE HYDROCHLORIDE, AND PENTAZOCINE. HOWEVER, THE UNDESIRABLE SIDE EFFECTS ARE LESS COMPARED TO THE ABOVE MENTIONED NARCOTICS ANALGESICS AND DRUG DEPENDENCE LIABILITY DOES NOT OCCUR. A PART FROM ITS PARENTERAL ANALGESIC ACTIVITIES, FLUNIXIN MEGLUMINE ALSO POSSESSES ANTI-INFLAMMATORY ATTRIBUTES. THE PRESENT WORK INCORPORATES ENVIRONMENTALLY FRIENDLY REACTION CONDITIONS WITH ASSOCIATED BENEFITS LIKE EXCELLENT YIELD, STRAIGHT FORWARD WORK UP, AND USE OF COPPER POWDER AS A CHEAP, READILY AVAILABLE, EFFICIENT AND SAFE CATALYST, WHICH ARE IMPORTANT FACTORS IN THE PHARMACEUTICAL INDUSTRY.

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APA: Copy

HOSSEINI, S.K., BAGHERPOOR, S., & YARHOSSEINI, M.. (2015). AN ECO- FRIENDLY ROUTE FOR SYNTHESIS OF FLUNIXIN MEGLUMINE. SEMINAR OF CHEMISTRY AND ENVIRONMENT. SID. https://sid.ir/paper/911299/en

Vancouver: Copy

HOSSEINI S.K., BAGHERPOOR S., YARHOSSEINI M.. AN ECO- FRIENDLY ROUTE FOR SYNTHESIS OF FLUNIXIN MEGLUMINE. 2015. Available from: https://sid.ir/paper/911299/en

IEEE: Copy

S.K. HOSSEINI, S. BAGHERPOOR, and M. YARHOSSEINI, “AN ECO- FRIENDLY ROUTE FOR SYNTHESIS OF FLUNIXIN MEGLUMINE,” presented at the SEMINAR OF CHEMISTRY AND ENVIRONMENT. 2015, [Online]. Available: https://sid.ir/paper/911299/en

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