EFFECTS OF ALOE VERA ON ADRENAL GLAND HISTOMETRY IN DIABETIC RATS

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ERFANI MAJD N.; SADEGHI N.; HOSSEINIFAR SH.

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Journal: SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL Year:2017 | Volume:13 | Issue:2 Page(s): 48-57

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Title

EFFECTS OF ALOE VERA ON ADRENAL GLAND HISTOMETRY IN DIABETIC RATS

Author(s)

ERFANI MAJD N. | SADEGHI N. | HOSSEINIFAR SH. | Issue Writer Certificate

Keywords

ALOE VERAQ2

DIABETESQ2

ADRENAL GLANDQ1

HISTOMETRYQ2

RATQ2

Abstract

ALOE VERAhas many applications in traditional medicine, also it has hypoglycemic effects. In present study, the protective effect of the ALOE VERA on the ADRENAL GLAND of the diabetic RATs were studied. Fifty mature male RATs at the age of 2-3 months old and weighing 200-250 g were randomly divided into 5 groups of 10 RATs each as follow: Group I which served as the control received no treatment, group II which received streptozotocin (IP) at the dose of 65 mg/kg to become diabetic. RATs with blood glucose more than 250 mg/dl were considered as diabetic. Group III diabetic RATs which received the ALOE VERA gel daily with a dose of 400 mg/kg. Group IV diabetic RATs which received insulin (10 units/rat). Group V received only ALOE VERA gel daily with dose of 400 mg/kg. On days 15 and 30 after the last ALOE VERA gel administration, blood glucose of all groups was measured. Animals were euthanized with ether. Then, ADRENAL GLANDs were collected and fixed in 10% neutral buffered formalin solution. The sections were stained using haematoxylin-eosin (H & E) stain, and histomorphometrical parameters were evaluated. The thickness of fasciculata layer and the size of the spongiocyte were significantly increased in the diabetic RATs (P£0.05). The thickness of fasciculate was significantly decreased in diabetic RATs which receivedALOE VERA and insulin (P£0.05). ALOE VERA has beneficial and protective effects on ADRENAL GLANDs in diabetic RATs.

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APA: Copy

ERFANI MAJD, N., SADEGHI, N., & HOSSEINIFAR, SH.. (2017). EFFECTS OF ALOE VERA ON ADRENAL GLAND HISTOMETRY IN DIABETIC RATS. SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, 13(2), 48-57. SID. https://sid.ir/paper/97079/en

Vancouver: Copy

ERFANI MAJD N., SADEGHI N., HOSSEINIFAR SH.. EFFECTS OF ALOE VERA ON ADRENAL GLAND HISTOMETRY IN DIABETIC RATS. SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL[Internet]. 2017;13(2):48-57. Available from: https://sid.ir/paper/97079/en

IEEE: Copy

N. ERFANI MAJD, N. SADEGHI, and SH. HOSSEINIFAR, “EFFECTS OF ALOE VERA ON ADRENAL GLAND HISTOMETRY IN DIABETIC RATS,” SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, vol. 13, no. 2, pp. 48–57, 2017, [Online]. Available: https://sid.ir/paper/97079/en

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