The purpose of this study was to review the effect of eight weeks strength training on serum levels of adiponectin and cholesterol of 16-18 years old boys.Method: For this purpose 24 male students (16-18 years old) with mean age 16.91±0.92 years, weight 74.19±5.50 kg and height 170.40±5.04 cm voluntarily selected after fill informed consent questioner from high school of Haj Jalil Fallahi of Marvdasht city. Then all subjects randomly divided into two groups: strength training and control. strength training group performed eight weeks of strength training (three days a week) with intensity of 60 -75% of one repetition maximum. There were eight stations in each training session and, each station was performed three sets. In pre and posttest session’s five CC fasting blood samples collected. For statistical analysis used independent and dependent t test (p£0.05).Findings: findings showed that eight weeks strength training has no significant effect on adiponectin (p=0.13) nevertheless induce significant reduction in total cholesterol (p=0.01).Conclusion: regard to finding of this research it concluded that noted training protocol was not effective on improvement of adiponectin nevertheless improved total cholesterol.

BACKGROUND AND OBJECTIVE: Identification of breast cancer risk factors is very important. Cholesterol by acting on tumor cells is considered as one of the risk factors for breast cancer. The conversion of cholesterol to bile acids is one of the major mechanisms of cholesterol excretion from body. In this study, total bile acids and cholesterol concentrations were evaluated in breast cancer patients.METHODS: In this case-control study, 109 of patients who breast cancer was confirmed by pathological examination and 109 healthy subjects who had normal physical exam and negative mammograms to rule out breast cancer were studied. Fasting serum total bile acids and cholesterol levels were measured enzymatically and then the data were analyzed.FINDINGS: The mean of total bile acids in breast cancer patients and control group were 11.67±0.92 and 13.36±0.81 mmol/l, respectively (p<0.05). Mean of cholesterol levels in breast cancer patients was 316.98±15.35 mg/dl and control group was 212.08±5.79 mg/dl (p<0.001). CONCLUSION: According to the results, it appears that lower amounts of body cholesterol are converted to bile acids in breast cancer patients.

Background and purpose: Coronary heart disease is one of the most common reasons for mortality in many countries. High lipid levels such as high total cholesterol are recognized as the risk factors for cardiovascular diseases. Various studies investigated the prevalence of dyslipidemia in Iran, so, in current study we performed a systematic review and meta-analysis of all studies assessing the prevalence of dyslipidemia in Iran.Materials and methods: The search was conducted using different databases such as Pubmed, SID, Magiran, Iranmedex, Irandoc, Medlib, and Google Scholar. The search keywords and terms included total cholesterol, prevalence, meta-analysis, and Iran. Finally 41 articles that were published during 1998- 2011 were selected. Assigning weights to the studies was done based on number of samples and the prevalence was investigated using binomial distribution. Data was analyzed applying random effects model in STATA (version 10) and R software. Also, publication bias was assessed by funnel plot.Results: Total number of samples in selected articles were 205913. Prevalence of total cholesterol ≥ 200 mg/dl was 38% (CI95%=30-46) which was 41% in male and 43% in female. The prevalence of cholesterol ³240 mg/dl (CI95%) was 17% (15-19); 15% in male and 18% in female. This prevalence was seen in both urban (18%) and rural (23%) areas.Conclusion: Precise information and knowledge on prevalence of lipid profile disorders could help clinicians and policy makers to plan for suitable interventional programs that decrease the prevalence of cardiovascular diseases.

In poultry, liver is the main organ in synthesis of lipids and their secretion into plasma. Secretion of lipids from liver and their storage in muscles is important in human nutrition. There are controversial reports about garlic effects on TC (total cholesterol) content of serum and liver in poultry. In this study the effect of diets containing various percents of garlic powder on TC content of serum, liver and muscles has been investigated. For this purpose, four groups (36 pieces each) of three- week male chickens were fed by diets containing 0, 1, 2 and 4 percent of garlic powder. At the end of 5th and 7th weeks 15 pieces of each group were bled and then scarifised. The liver, pectoral and femoral muscles TC content were extracted and measured by specterphotometric method. Results showed that all diets containing 1%, 2%, 4% garlic had no effect on TC of Serum, muscle and liver at the end of 5th week, while at the end of 7th week, 2% and 4% diets, in liver and 4% diet in serum and muscles, significantly decreased TC in comparison with control (P<0.05) respectively. It was concluded that, simultaneous reduction in serum, liver and muscle TC content, may be due to inhibition of hepatic TC synthesis and or secretion as a dose dependent manner.

Introduction: Lipid level variations are among the most important risk factors for cardiovascular disease. Apolipoproteins play a the key role in lipid metabolism. In the present study the association of XbaI apolipoprotein B polymorphisms on lipid variation was examined. Materials and Methods: A cross-sectional study was conducted on 849 subjects from the Tehran Lipid and Glucose Study population. Blood pressure was measured and the body mass index was calculated. TG, Chol, FBS, HDL-C and its subfractions, Apo B and Apo A1 levels were measured, and LDL-C concentration was calculated. A segment of the apo B gene was amplified by PCR and the polymorphism was revealed by RFLP using XbaI restriction enzyme.Results: Allele frequencies obtained for X+and X- were 27.6 % and 72.4%, respectively and were in the Hardy- Weinberg Equilibrium (HWE). The presence of the X+allele was significantly associated with increased total cholesterol (X+X+: 193±1.2 mg/ml vs. X-X-: 182±1.2 mg/ml, P 0.022) and apolipoprotein B (X+X+: 116±1.5 mg/ml vs. X-X-: 104±1.4 mg/ml, P 0.024). The associations were significant even after adjustment for age, sex, BMI, smoking, diastolic and systolic blood pressure and fasting blood sugar.Conclusion: The observed allele frequencies were similar to other studies.Considering the association of XbaI polymorphisms with lipids factors, it is important to examine the relationship of Apo B gene variation and similar gene with lipids metabolisms.