The objective of this research was to study genotypexenvironment interaction and to evaluate stability analysis of grain yield in chickpea genotypes under rainfed condition. Experimental material was comprised of 17 genotypes with the experiments carried out in RCBD of four replications at Kermanshah, Lorestan, Ham, Gachsaran and Gorgan Research Stations during the two years of 2003-2004. The results of combined analysis showed that yearxlocation, genotypesxlocation and yearxlocationxgenotypes were significant. Different stability analysis methods employed for assessing yield stability. Using environmental coefficient of variation, it was (CVi) indicated that genotypes no. 1,7, 13, 15 and 17 with high yielding and less variations may be identified as stable genotypes. Through Rank Sum of Method (RSM) it was found that genotypes number 7, 13 and 5 were the most stable lines. In addition, results of stability analysis on grain yield (using simultaneous selection for yield and stability as well as Shokla variance (si2) showed that genotype no.13 was the most stable genotype. Stability analysis determined through AMMI stability value (ASV) method showed that genotype no.13 (FLIP 97- 114) was the most stable one. All in all and based on different stability analysis methods it was shown that genotype no. 13 was the most stable genotype. The results of different stability parameters were found to be similar for the selected genotypes. But AMMI stability value (ASV) was found to be a more valuable and practical approach to stability analysis in compare to others, for ASV parameter explained %76 of the genotype x environment sum of squares.

one of the most commonly encountered issues associated with open heart surgery is the extended duration of endotracheal intubation, as well as the complexity of the subsequent weaning process from mechanical ventilation. It has been demonstrated that as the period of mechanical ventilation is prolonged, patients tend to experience an increasing number of side effects and complications related to this extended support. An effective strategy during this phase is essential for facilitating patient recovery[1]

Quantitative and qualitative traits and stability of marketable tuber yield of 14 promising potato clones, along with three commercial cultivars (Agria, Marfona and Savalan) as checks, were evaluated at the Ardabil Agricultural and Natural Resources Research Station during 2013 and 2014. The experiment was based on a randomized complete block design with four replications. During growing period and after harvest, traits like main stem number per plant, plant height, tuber number and weight per plant, total and marketable tuber yield, dry matter percentage, baking type, hollow heart, tuber inner ring and discoloration of raw tuber flesh after 24 hours were measured. Combined ANONA for quantitative traits showed that there were significant differences among promising clones as to total and marketable tuber yield, tuber number and weight per plant, plant height, tuber mean weight, main stem number per plant and dry matter percentage and their interactions with year in total and marketable tuber yield. The clone 9 (397078-3) with the least amount of marketable tuber yield had significant difference with clones 4 (397045-13), 1 (397031-16), 3 (397031-11), 6 (397009-8) and 12 (397067-6) in 2013 and with clone 4 (397045-13) and Agria cultivar in 2014. The clones 4 (397045-13), 1 (397031-16) and 12 (397067-6) had uniform tuber, yellow to dark-yellow skin and light-yellow to yellow flesh color, tuber shape of oval round and round, shallow to mid shallow eyes, no tuber inner ring, hollow heart and tuber inner crack and mid-late maturity. They were selected for home consumption of chips, french-fries and frying. Based on the results of factor analysis, "tuber yield", "number of tuber" and "plant structural and quality" were named as first, second and third quality determining factors respectively. In this experiment, GGE Bi-plot model and AMMI Stability Value (ASV) parameter, were acceptable methods for the selection of marketable tuber yield stability which found to be simultaneously could introduce clones 1 (397031-16), 3 (397031-11), 4 (397045-13) and 12 (397067-6) to be selected as stable clones with high marketable tuber yield.

Extended Abstract Background: Cumin (Cuminum cyminum L.) is an aromatic, annual herbaceous plant from the Apiaceae family. Cumin is one of the tolerant medicinal plants to water deficit conditions with a short growth period, which can produce acceptable and economic yield under water deficit conditions. This plant is currently the second most used spice in the world after pepper (Pepper nigrum), suggesting its high importance. This experiment aimed to evaluate ecotypes, planting dates, and relationships between ecotypes and planting dates and to identify high-yield cumin stable ecotypes using AMMI and GGE bi-plot methods. Methods: The stability of the grain yield of seven cumin ecotypes (Bardascan, Birjand, Taibad, Davarzan, Ferdos, Salehabad, and Nehbandan) was investigated in an experiment based on randomized complete blocks design with three replications in four planting dates (November 6, December 6, January 5, and February 5) at the research farm of the Southern Kerman Agricultural and Natural Resources Research and Education Center during 2020-2021 crop year. The seeds were planted by hand on the rows at a depth of 1 cm with a distance of 5 cm from each other. The distance between the rows was 20 cm. Seeds were irrigated with the drip method, and weeds were controlled by hand. The plants were harvested after physiological maturity, and the grains were separated from other organs and recorded as the grain yield of each plot. The yield stability of the ecotypes was analyzed using the AMMI model, and the first and second interaction components of AMMI (IPCA1 & IPCA2) were used as stability parameters for the ecotypes and the planting dates (environments). The GGE bi-plot method was used to analyze the obtained data, interpret the ecotype and planting date interaction, and determine mega-environments. Results: The results of compound variance analysis showed significant effects of the environment (planting date), ecotype, and the interaction of planting date × ecotype. Due to the significance of the environmental effect and the justification of 80% of the variation by this effect, as well as the significance of the planting date × ecotype, stability analysis of grain yield was conducted for ecotypes in different planting dates. The results of AMMI analysis showed that the two components, IPCA1 (AMMI 1) and IPCA2 (AMMI 2), included 93.56% of the total variance of the genotype × environment interaction. The AMMI stability value (ASV) was used for the simultaneous use of all components. The ASV statistic indicated that the Nehbandan ecotype with the lowest value (1.91) was the most stable ecotype, and the Ferdos and Salehabad ecotypes with the highest ASV value were the most unstable ecotypes. The results of the GGE biplot method revealed that the first and second principal components accounted for 93% of the total variation related to the ecotype and planting date interaction, which indicated the validity of the GGE-biplot analysis. Based on GGE biplot results, planting dates of November 6 and December 6 were in the same megaenvironment and produced the highest grain yield. Similarly, the two planting dates of January 5 and February 5 were in the same megaenvironment and produced the lowest grain yield. The graphs showed that the Ferdos ecotype had high special adaptability with the planting dates of November 6 and December 6, and the Birjand and Davarzen ecotypes had high special  adaptability with the planting dates of January 5 and February 5. The Taibad, Salehabad, and Nehbandan ecotypes had no special compatibility with the studied planting dates. Ferdos and Birjand ecotypes had a higher average grain yield than the other ecotypes, but they were placed in the group of ecotypes with low stability due to their distance from the AEC line. The Nehbandan was the most stable ecotype due to its adjacency to the AEC line, but it produced a low grain yield. In addition, the results of the GGE bi-plot showed that the Birjand was the closest ecotype to the ideal genotype hence it was considered the most desirable ecotype. Bardascan, Ferdos, and Daverzan ecotypes were the ecotypes in the next ranks in terms of desirability, and Salehabad and Taibad ecotypes were identified as undesirable ecotypes due to their greatest distance from the ideal genotype. Conclusion: The results of compound variance analysis showed significant effects of the environment (planting date), ecotype, and the planting date × ecotype interaction effect. The biplot results of AMMI analysis showed that the Nehbandan ecotype was the most stable and Ferdos and Salehabad ecotypes were the most unstable ecotypes. This was also confirmed through the ASV. The results of the GGE bi-plot indicated that the planting dates of November 6 December 6 with the highest average grain yields were located in a mega-environment, and the two January 5 and February 5 planting dates, with the lowest average grain yields, were also located in the same mega-environment. This can indicate the determination of the time range of the planting date to obtain an acceptable yield, although the yield decreased with a delay in planting. Finally, the figure showed that the Nehbandan was the most stable ecotype with below the average yield, and Birjand was the most ideal ecotype. Therefore, it can be concluded that the Birjand ecotype cultivation not only produces a high yield but also has high relative stability.

Background: Snakebite is a potentially life-threatening emergency that can be treated effectively. Snake envenomation can cause hematologic and coagulation abnormalities. In this respect, tests such as prothrombin time (PT), international normalized ratio (INR), and activated partial thromboplastin time (aPTT) are commonly used. The present study aimed to determine the value of coagulation parameters in the prognostication of snakebite patients. Methods: This prospective descriptive observational study examined the coagulation parameters, including PT, INR, and aPTT, in consecutive cases of snake envenomation admitted to a tertiary health care hospital from October 2019 to August 2021. The correlation of coagulation parameters with each other and with prognostic indicators (ie, the number of days spent in the intensive care unit [ICU], the requirement of anti-snake venom [ASV], fresh frozen plasma [FFP], and the total number of blood products) was studied. Results: A total of 58 patients with snakebite were studied. The majority were males (69%). The highest proportion of patients belonged to the age group of 16-40 years (60%). The correlation of coagulation parameters with each other was statistically significant. The correlation of coagulation parameters with prognostic indicators (ie, the total number of ASV vials administered, the total number of days in the ICU, the total number of FFP units administered, and the total number of blood components administered) was statistically significant. Conclusion: Coagulation parameters (PT, INR, and aPTT) are essential laboratory investigations for treatment monitoring and can be used effectively for the prognostication of snakebite patients. In cases where the coagulation profile of snakebite patients shows abnormalities, conducting repeated coagulation studies at intervals of 12 hours can contribute to improved prognostication.

Tests were done to determine high-yielding and stable durum wheat genotypes. An experiment was set up as a RCBD (Randomized Complete Block Design) with three replications on 17 advanced durum wheat genotypes under rainfed and supplementary irrigation conditions in the cropping seasons of 2011-13. Combined analysis of variance indicated that environment main effect accounted for 70.09% of total yield variation; and effects of genotype and Genotype×Environment Interaction (GEI) accounted for 2.95 and 10.71%, respectively. Results indicated remarkable difference in genotypes response across environments. G×E interaction was analyzed following Additive Main effects and Multiplicative Interaction (AMMI) model. The first two interaction Principal Component Axes (IPCA1 and IPCA2) explained 53.75 and 36.99% of total interaction effects, respectively. Based on the AMMI model, AMMI Stability Value (ASV) and Genotype Selection Index (GSI), genotypes G11, G8, and G14 were selected for all environments. According to the AMMI2 biplot, the G15, G16 and G17 exhibited specific adaptation with rainfed (E1) and irrigation (E2) environments. G3 and G4 displayed specific adaptation with rainfed (E3) environment and G10, G9, G1, and G12 indicated specific adaptability with irrigation (E4) environment. The E3 had high discrimination ability, so, this environment was considered sufficient for making genotypes recommendation. Results of this investigation illustrate that the AMMI stability parameters are suitable for characterizing stable genotypes and that the GSI parameter can detect genotypes with high grain yield and good stability for plant breeding research in durum wheat.

Background and Objective: Selection of wheat cultivars with stable seed yield and seed yield components in different climatic conditions was aim of this research. Methods and Materials: To evaluate the seed yield and seed yield components stability of 20 spring wheat lines, this experiment was done using RCBD with two replications under five conditions for three years(2010-2013) in Islamic Azad University research stations( Tabriz and Mianeh). Results: Due to significant Genotype X Environment interaction (G X E), stability analysis for seed yield and seed yield components was done using AMMI method (Additive Main effects and Multiplicative Interaction) and the results showed that the lines N-75-4, N-75-5, N-75-17 and N=75-1 are the stable for 1000KW, respectively, the lines N-75-6, N-75-4, N-75-1, N-75-9 and N-75-14 are the most stable for number of seed per spike, the lines N-75-6, N-75-16, N-75-1 and N-75-5 have stability of producing spike per square, respectively, and the lines N-75-6, N-75-5, N-75-1 and N-75-17 have stable seed yield, respectively. Conclusion: According to the results of AMMI method the lines N-75-1(Tajan), N-75-5 (Yang87-158) and N-75-6 (Rayan 89) with the seed yield of 6. 475, 5. 623 and 4. 083 t/ha had the most stability respectively, so on the basis of having the stable yield and seed yield more than average of total lines, those lines can be used as a parental lines in wheat breeding program and secondary can be cultivated in the spring in cold regions of East Azerbaijan and similar places also.

2Abstract Aim. This study aimed to compare the effect of Adaptive Support Ventilation (ASV) and Synchronized Intermittent Mandatory Ventilation-Pressure Support (SIMV-PS) modes on consequence of weaning off patients from mechanical ventilator after coronary artery bypass surgery Background. The ventilation mode used for respiratory support in patients after coronary artery bypass graft surgery is very important. In addition to avoiding pressure on patient's sternotomy incision, the ventilation mode should also provide the possibility of rapid weaning of patient to avoid complications caused by long-term ventilation. Method. In a semi-experimental study, 26 patients were ventilated with ASV as the experimental group and 26 patients were ventilated with SIMV-PS mode as the control group after coronary artery bypass graft surgery in Rajaie Cardiovascular Medical and Research Center, Tehran, Iran. Mechanical ventilation time and endotracheal tube removal time, hemodynamic variables, and arterial blood gas analysis were compared between the two groups. Data were analyzed using an independent t-test, repeated measures ANOVA and chi-square. Findings. Out of 52 patients, 36 (69.2 percent) were male and 16 (30.8 percent) were female. The mean time for the endotracheal tube removal was 89.42±33.83 minutes in the experimental group and 101.53±44.91 minutes in control group, which did not have a statistically significant difference (p=0.843). The mean duration of mechanical ventilation of patients in the experimental group was 483.84±158.153 minutes and in the control group, it was 541.92±257.81 minutes, which were not statistically different (p=0.332). Conclusion. The use of ASV mode for mechanical ventilation after coronary artery bypass graft did not affect reducing the duration of mechanical ventilation and the time of endotracheal tube removal compared to SIMV-PS mode. Therefore, the use of ASV mode for respiratory support of patients undergoing coronary artery bypass surgery should be considered according to the patient's condition and the nurses' expertise.

Background: Suitable mechanical ventilation strategies can reduce the incidence and severity of ventilator‑ associated lung injury in patients with acute respiratory distress syndrome (ARDS). In this study, the effects of adaptive support ventilation (ASV) and synchronized intermittent mandatory ventilation (SIMV) on respiratory parameters and arterial blood gases (ABGs) parameters were compared in ARDS patients. Materials and Methods: Twenty‑ four patients were randomly divided into two groups of ASV and SIMV. Patients were followed up for 3 days, and respiratory parameters including rapid shallow breathing index (RSBI), spontaneous breathing rate (SBR), minute volume, and peak inspiratory pressure (PIP) as the primary outcomes and ABG parameters including PaO2, FiO2, PaCO2, HCO3, and PaO2/FiO2 ratio as the secondary outcomes were measured. Results: PIP in patients in the SIMV group on the 1st day (P = 0. 013), 2nd day (P = 0. 001), and 3rd day (P = 0. 004) was statistically significantly more compared to those in patients in the ASV group. RSBI, SBR, and minute volume between the ASV and SIMV groups during the 3 days were not statistically significantly different (P > 0. 05). The mean arterial blood pressure, heart rate, PaO2, and PH between both groups were similar (P > 0. 05). At the end of the 2nd and 3rd days, the level of FiO2 and PaCO2 in ASV was significantly lower than those in ASV group. HCO3 in each of the 3 days in the ASV group was statistically significantly lower than that in the SIMV group (P < 0. 050). PaO2/FiO2 ratio in patients in the ASV group in the 3 days was statistically significantly higher than that in the SIMV group (P < 0. 050). Conclusion: By reducing PIP and improving oxygenation and ABG parameters, ASV mode may be a safe and feasible mode during mechanical ventilation in patients with ARDS.

Background: Different modes of mechanical ventilation are used for respiratory support after coronary artery bypass graft (CABG). This study aimed to compare the effect(s) of using adaptive support ventilation (ASV) and synchronized intermittent mandatory ventilation (SIMV) on the length of mechanical ventilation (intubation duration) and hospital stay after coronary artery bypass graft surgery.Materials and Methods: In a randomized control trial, 64 patients were ventilated with ASV as the experiment group or with SIMV as the control group after CABG surgery in Chamran Hospital of Isfahan University of Medical Sciences. The time of tracheal intubation and the length of hospital stay were compared between the two groups. Data were analyzed and described using statistical analysis (independent t‑test).Results: The mean time of intubation duration was significantly lower in ASV group compared with SIMV group. (4.83 h vs 6.71 h, P < 0.001). The lengths of hospital stay in the ASV and the SIMV groups were 140.6 h and 145.1 h, respectively. This difference was significant between the two groups (P = 0.006). Conclusions: According to the results of this study, using ASV mode for mechanical ventilation after CABG led to a decrease in intubation duration and also hospital stay in comparison with the SIMV group. It is recommended to use ASV mode on ventilators for respiratory support of patients undergoing coronary artery bypass graft surgery.