introduction: As the population grows older and more obese, Hypertension eventually develops in more people during their life span. The prevalence of kidney stone disease is estimated at 1% to 15%, varying in degree according to age, gender, race, and geographic location. The objective of this study was to determine the frequency of nephrolithiasis in hypertensive patients.materials and methods: Using simple non probability sampling, a total of 200 patients who referred to Aria and Bahman 22nd Hospitals entered this study. The exclusion criteria were determined as: those subjects that had used carbonic anhydrase or thiazide; those who had a history of surgery on their urinary system; those who had been diagnosed with HTN before affected by nephrolithiasis. The main group was divided into 2 groups: Group 1 who had normal blood pressure (control group) and group 2, hypertensive patients (case group). All the patients were examined using both ultrasound and supine abdominal X ray (KUB) for stone scanning. Then, statistical analyses were conducted using t-test, chi-square test and Fisher’s Exact Test. All the subjects signed a testimonial before the test.results: The comparison of sex and age distribution between the case and the control groups showed no significant differences. Also, the results of Ultra sonograms showed echogenic density of the urinary system prevailing in 4.2% of the patients in the control group and in 25% of those in the hypertensive (case) group (P<0.05). Moreover, KUB revealed significantly lower frequency of stone density in kidneys in the control group (4.2%), as compared to the hypertensive group (21%). As a whole, nephrolithiasis was observed in 4% of the patients in the control group and 21% in those subjects in the hypertensive group. Such a difference between the two groups was statistically significant (P<0.001).conclusion: We believe that urinary stone is significantly more frequent in hypertensive subjects than normal subjects.

Background: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver condition that is associated with sedentary lifestyle and inappropriate feeding habits. The main purpose of this study was to evaluate the effect of 12 weeks of combined training with dietary approaches to stop Hypertension (DASH) diet on alanine transaminase (ALT) enzyme levels, liver fat, and anthropometric indices in patients with NAFLD. Methods: This was an interventional, double-blind randomized clinical trial study with two arms, DASH diet and DASH diet with combined exercise. Patients in both groups received the relevant diet under the supervision of a specialist, and patients in group 2 performed the selected combination exercise according to the schedule. Variables were measured at specific times. Findings: The consumption of DASH diet and combined exercise significantly reduced the mean liver fat, weight and waist to hip index (WHR) in both groups. ALT enzyme showed a significant decrease in exercise group (P < 0. 050). Conclusion: According to the findings, consumption of DASH diet and combined exercise can improve some indicators in patients with fatty liver.

Hypertension is a major risk factor for myocardial infarction, heart failure, stroke, peripheral arterial disease, and aortic aneurysm, and is a cause of chronic kidney disease. Hypertension is often associated with metabolic abnormalities such as diabetes and dyslipidemia, and the rate of these diseases is increasing nowadays. Recently it has been hypothesized that oxidative stress is a key player in the pathogenesis of Hypertension. A reduction in superoxide dismutase and glutathione peroxidase activity has been observed in newly diagnosed and untreated hypertensive subjects, which are inversely correlated with blood pressure. Hydrogen peroxide production is also higher in hypertensive subjects. Furthermore, hypertensive patients have higher lipid hydroperoxide production. Oxidative stress is also markedly increased in hypertensive patients with renovascular disease. If oxidative stress is indeed a cause of Hypertension, then, antioxidants should have beneficial effects on Hypertension control and reduction of oxidative damage should result in a reduction in blood pressure. Although dietary antioxidants may have beneficial effects on Hypertension and cardiovascular risk factors, however, antioxidant supplementation has not been shown consistently to be effective and improvement is not usually seen in blood pressure after treatment with single or combination antioxidant therapy in subjects thought to be at high risk of cardiovascular disease. This matter is the main focus of this paper. A list of medicinal plants that have been reported to be effective in Hypertension is also presented.