Introduction: Use of different methods for GnRH administration in ART cycles is a controversy.Microdose regimens in poor- responder patients are very useful and this has been determined by some studies, but it is not clear how this regimen affects patients with first (IVF/ICSI) cycle. Materials & Methods: In a prospective, randomized, clinical trial study at The Research and Clinical Center for Infertility and Madar Hospital, Yazd, we compared 140 patients who were candidates for IVF/ICSI for the first time. 70 patients received Microdose flare (A Group) and 70 patients were administered GnRH in long luteal phase (B group). Number of oocytes, follicles, embryos and the pregnancy outcome were compared in both groups. In microdose group, after administration of 21 contraceptive pills in the last cycle from day 3 , GnRH was given to patients ( 0.05 cc twice a day) and H MG from day 5 (3 vials a day). In long protocol, the patients received 0.5 cc Buserelin daily from day 21 subcutaneously and with the beginning of bleeding , the dosage was decreased to half. HMG was given three times a day. As the follow up of some patients was difficult and their pregnancy outcome was unknown, 14 patients of A group and 3 patients of B group were left out from the study. The data was analyzed by chi-square and T test. Results: Number of oocytes, embryos and outcome of pregnancy were not different the in two groups. However, the number of mature follicles in long method was higher but not significant statistically. Conclusion: The Microdose flare regimen thus offers no further advantage for patients with first cycle of IVF/ICSI.    

The effects of pH (4,4.5 and 5), inoculum level (102 and 104), temperature (5,15,25,35 and 45 0C)and type of the food (barley or mushroom soup) on lag phase of growth of Staphylococcus aureus in packet commercial Iranian soups (barley and mushroom) were evaluated as a factorial design study. The lag phase of growth of this bacteria was affected significantly (P<0.05) by the variables of "Temperature", "Inoculum" and 2-way interaction of "Inoculum x Temperature" but not by kind of soup used in this study. Regression equation was derived relating lag phase of growth to "Temperature", "Inoculum" and 2-way interaction of "Inoculum x Temperature". From this model the values of predicted tag phase of growth of Staphylococcus aureus can be calculated from any combination of the factors in this study (R2 = 0.952).

Putrefactionin causes unpleasant odors, undesirable changes in taste, color and texture, and reduced nutritional value. at usage of active coating that contain antimicrobial agents ̨ many factors should be considerable. Most of these factors depend on the chemical nature of the antimicrobial agent, the type of food and the target microorganism. In this study, investigated̨ the chemical and microbial properties of Rainbow trout fish that Coated with Curcumin Nanomulsion. The prepared samples are divided into 4 groups, which include control treatment, nanoemulsion containing 1, 3 and 5% curcumin. In order to investigate the effect of treatments on the chemical properties ̨ pH and free fatty acid and total volatile basic nitrogen, were measured. Microbial characteristics were evaluated through microbial total count, fecal coliforms and coagulase-positive Staphylococcus aureus. Also for sensory evaluation by panelists ̨ odor, texture, color and fish general acceptance were evaluated. The results of this study showed that by using nanoemulsion coating that include 5% curcumin, the shelf life of the fish could be increased for 10 days, with favorable chemical and microbial properties.