Background and objectives: Chickpea (Cicer arietinum) is the third most important pulse crop in the world, grown widely across Asia and the Middle East. Weed is one of the main limiting factors in Chickpea production. Several characteristics of chickpea, such as slow plant emergence, short plant height, and chickpea morphology allow weeds to compete effectively.Materials and methods: To investigate the effect of weed interference duration and fertilizer type on yield and yield components of chickpea (cv. Hashem) grown under two different production system, a field experiment was conducted at Sabzevar in 2013-2014. Experiment was conducted as split plot in a randomized complete block design with three replications. Experimental factors were chemical and organic fertilizer application as the main plots and duration of weed interference (0, 2, 4, 6 and weeks after emergence 8 (weedy)) as sub plots. Agronomy management in chemical fertilizer application system including plowing with Moldboard, use of chemical fertilizers based on soil test and non-seed inoculation and in organic fertilizer application system including Chisel plowing, application 3 t ha-1 compost, seed inoculation and foliar application with organic liquid fertilizer. Other agricultural operations were similar in both tillage systems.Results: Analysis of variance showed that cultivation system had significant effect on number of branches, number of pods per plant, number of seeds per pod and economic yield whereas plant height and biological yield was not affected by cultivation system. Weed interference duration statistically influenced all traits except for weed density and plant height. Cultivation system and weed duration interaction had significant effect on weed dry matter, plant height, number of branches, number of pods per plant, number of seeds per pod and economic yield. Organic fertilizer application system had 13.24% and 59.47 lower weed density and weed dry matter compared with chemical fertilizer application system, respectively. In organic fertilizer application system, Chickpea had more plant height, number of branches, number of pods per plant, number of seeds per pod, biological and economic yield than chemical fertilizer application system. Increasing of interference duration was decreased plant height (17.21%), lateral branches (33.34%), number of pods per plant (61.79%), and number of seeds per plant (73.12%), biological yield (54.25%) and economic yield (77.22). Study of logistic regression function coefficients fitted to yield reduction showed that the onset of yield loss was occurred at 24.5 days after emergence in chemical fertilizer application system while in organic fertilizer application system the onset of yield loss was postponed to 31.64 days after emergence.Conclusion: In conclusion, results showed in both chemical and organic fertilizer condition, weed interference decreased economic yield. In organic fertilizer application system, weed interference until four weeks and in chemical fertilizer application system, weed interference until two weeks after pea emergence did not have significant reduction on yield.