Objectives: The aim of present project was to determine the relation between sexual dysfunction and psychiatric disorders in women at a psychiatric clinic. Method: This research was a case-control one. The case study group was consisted of 165 subjects referred by a psychiatric outpatient clinic. They were diagnosed with depression, anxiety, phobia, aggression, and psychosomatic problems; there were 33 patients in each group.33 visitors and acquaintances of the patients composed the control group. They were selected through convenient sampling; none had a previous psychiatric history, nor did they consume any psychotropic medications. To collect data, interviews and questionnaires were used. The evaluative instruments included a demographic questionnaire, sexual dysfunction disorder questionnaire, and SCL-90-R. Findings: The results showed that there was a significant difference in distribution of cases of sexual dysfunction disorder between the case group and the control group. This difference was also noted between patients with depression and control group, and patients with somatic problems and control group. Furthermore, there was a significant difference between the case group and the control group in sexual desire and orgasm disorders. Results: Sexual disorder was found more in patients of psychiatric clinics than the normal population.