Dermatology and Cosmetics
Year:2018 | Volume:8 | Issue:4 |Papers Count:9

Background and Aim: Cosmetic surgery is performed to change the appearance of people and improve their self-esteem and according to the available reports, Iran ranked first in cosmetic surgery. The aim of this study was to determine the socio-cultural attitudes about cosmetic surgery and its related factors among female students of Hamadan University of Medical Sciences.Methods: This cross-sectional study was carried out on 340 female students of Hamadan University of Medical Sciences in 2017 with a stratified sampling method. To gather data, we used socio-cultural attitudes questionnaire and recorded demographic variables. Data were analyzed with SPSS 24 software using t-test, ANOVA and linear regression tests.Results: The age group of 21-30 years were the most frequent participants (56.7%). Most of the students were medical students (24.4%). They often received information about cosmetic surgery via the internet (63.2%). There were significant statistical relationships between social and cultural attitudes with the field of study and father's job (P<0.05). The results of regression analysis showed that the variables of the father's job and body mass index evaluation predicted the social and cultural attitudes.Conclusion: It is recommended to conduct similar studies other universities of the country and compare them with the findings of this research.

Background and Aim: Oral cancer as the most common cancer of head and neck region holds the eighth rank among all cancers in order of prevalence. More than 90% of oral cancers are of squamous cell carcinoma (SCC). The main objective of this study is the determination of the survival rate in patients with oral SCC and the factors influencing thereon.Methods: In this study, 174 recorded cases of patients with oral SCC were evaluated. Required data on survival of patients were gathered by phone calls. Using software SPSS 20, the statistical analysis of data was carried out. The survival rate of the patients and the corresponding influential factors were analyzed by the Kaplan-Meier curves and Cox regression tests, respectively.Results: 57.6% of the patients were male. The age of the patients ranged between 22-89 years with the average onset age of 61.5 years. The most common site of oral SCC was tongue. The overall five-year survival rate of the patients was 49.4%±0.05. The survival rate had a statistically significant relation with age of the patients and their treatment methods, including surgery or chemotherapy.Conclusion: The prevalence of oral SCC is higher in men and overall survival rate decreases with increasing age of the patients. Due to the low survival rate of oral cancer patients, more attentions should be paid to this condition.

Background and Aim: Curcumin possesses diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. The aim of this study was to develop liposomal formulation of curcumin and evaluate the leishmanial effects of its topical use against L. major in vitro and in vivo.Methods: Nanoliposomes containing 1, 2 or 3% curumin were prepared by fusion method and characterized for their size, morphology and stability. The in vitro efficacy of liposomal form of Curcumin against promastigotes and amastigotes form of L. major was also evaluated. Moreover, the leishmanial effect of formulations was evaluated in infected BALB/c mice. The lesions were treated topically by different formulations twice a day, for 4 weeks. During this time and 4 weeks after treatment, lesions size was measured every week. The level of splenic parasite burdens was investigated in week 4 after parasite inoculation.Results: Curcumin showed no leishmanicidal effect against live promasigotes and amastigotes in culture media. There was no significant difference between treated and control animals regarding lesion size and splenic parasite burden.Conclusion: The results of this study showed that nanoliposomes containing curcumin in topical form has no significant leishmanicidal effect in vitro and in vivo against L. major.

The skin is the largest organ of the human body, the first protective barrier of the body and one of the important excretory organs. In conventional medicine, there is great focus on skin rashes to help to diagnose the internal illnesses. Persian medical scholars have also studied a wide range of internal disorders by examining skin manifestations. The aim of this study is to investigate the etiology and semiology of various skin rashes and manifestations from Persian and conventional medicine viewpoints, and to clarify similarities and differences between them. For this purpose data corresponding with key words was extracted from reference books and then relevant scientific databases including Google scholar, PubMed, Web of Science, Scopus and reliable sources like Janquira histology, Habif and Savin's dermatology books were examined. An overview of the cutaneous rash and diseases, revealed that in many cases, these two schools of medicine are not comparable. However, in some cases, such as etiology, description, clinical signs, diagnosis, etc., serious similarities in topic of rashes, skin manifestations and chronic diseases are mentioned in the overview of this two medical schools.

Diseases of the skin can cause harm and emotional distress in patients. The desirable drug is one with least complications and most effectiveness. By prolongation of target exposure, drug effectiveness could be improved. There are several suggested solutions, including the use of chemical enhancers, electroporation, iontophoresis, and the use of nanoparticles as carriers of pharmaceutical agents. The use of various nanostructures, including liposomes, dendrimers, autosomes, and many mineral nanoparticles, have been proposed to prevent the limitations with conventional formulations. Topical drug delivery has many benefits, including using high concentrations of the drug and reducing systemic passage of medicament. Many skin products, such as Estrasorb, Diractin and Aczone are available in the market with new and different manufacturing techniques for more skin penetration.This paper introduces new approaches to drug delivery, types of nanocomposites and methods for increasing the penetration of pharmaceutical agents in the skin. Various factors such as physicochemical properties and the size of nanoparticles, as well as the effects of manipulation on the surface of these particles, have been discussed.

Application of sunscreens is one of the most important ways for skin protection against sunburn, early skin aging and skin cancer.Due to variety of sunscreen products, it is necessary to assure their protection ability against the suns damages. Performance assessment of sunscreens against UVB expressed by sun protection factor. Due to great cost of determination methods of this factor in foreign countries, developing a comprehensive protocol for in vivo SPF determination in Iran would have distinct benefits.In this study four international standards have been reviewed and compared for Sun Protection Factor (SPF) determination including ISO24444, FDA2011, AS/NZS 2604: 2012 and CEN 2006. The general process of in vivo SPF determination is similar in these protocols but there are some obvious differences in details that leading to advantages and disadvantages for each of them.In this study a complete document were collected, then regarding to available facilities and with cooperation of Iran food and drug organization a comprehensive in vivo SPF determination protocol will be developed.

Introductio: Intravascular papillary endothelial hyperplasia (Massons hemangioma) is an unusual, benign, non-neoplastic, vascular lesion. The lesion is a vascular proliferative reaction following traumatic vascular stasis.Case Report: In our case a submandibular lesion occurred after insect bite and pathology confirmed it as Masson hemangioma.Conclusion: Post traumatic red-blue firm lesions should be evaluated pathologically for many differential diagnosis including rare cases such as Masson, s hemangioma.