The most part of success or failure of educational programs depends on the thought, attitude, and the meaning the teachers mean their work by. Therefore the present study with correlational design aimed at exploring the relationship among philosophical spirit, spiritual quotient and high school teachers’ teaching quality in Babol. The statistical population included all second grade female teachers of second level of high school (N= 300) and their students (N=1617) in the academic year of 2014-2015. In current study, a teaching quality questionnaire adopted from Siraj Teaching Quality Questionnaire (2002), a researcher-made questionnaire on philosophical spirit, and a Spiritual quotient Questionnaire developed by Badie et al. (2010) were used. Kolmogorov-Smirnov test, Pearson correlation coefficient, and stepwise regression analysis were manipulated in the inferential analysis. Results indicated that philosophical spirit and spiritual quotient were significantly and positively correlated with teaching quality and philosophical spirit was significantly and positively related to spiritual quotient. Among dimensions of philosophical spirit, advocacy of human values, curiosity¸ innovativeness, and contemplation and among dimensions of spiritual quotient, addressing moral virtue and general thoughts and belief aspects could predict teaching quality.